The perceptual significance of the cochlear amplifier was evaluated by predicting level-discrimination performance based on stochastic auditory-nerve (AN) activity. Performance was calculated for three models of processing: the optimal all-information processor (based on discharge times), the optimal rate-place processor (based on discharge counts), and a monaural coincidence-based processor th...

We comprehensively evaluated particle lidar ratios (i.e., particle extinction to backscatter ratio) at 532 nm over Wuhan in Central China by using a Raman lidar from July 2013 to May 2015. We utilized the Raman lidar data to obtain homogeneous aerosol lidar ratios near the surface through the Raman method during no-rain nights. The lidar ratios were approximately 57 ± 7 sr, 50 ± 5 sr, and 22 ± ...

Pulsed laser deposition was used to grow Sr(2)FeMoO(6) films of different thicknesses on MgO(100), SrTiO(3)(100), and LaAlO(3)(100) with respective lattice mismatches of +6.2%, -1.2%, and -4.3%. Surface roughness and morphology, and film crystal quality and epitaxy were determined by atomic force microscopy and x-ray diffraction, respectively. Two-dimensional layer-by-layer growth was evident f...

Chemically skinned single fibers from adult rat skeletal muscles were used to test the hypothesis that, in mammalian muscle fibers, myosin heavy chain (MHC) isoform expression and Ca(2+)- or Sr(2+)-activation characteristics are only partly correlated. The fibers were first activated in Ca(2+)- or Sr(2+)-buffered solutions under near-physiological conditions, and then their MHC isoform composit...

We have developed a quantitative model for the creation of cytoplasmic Ca gradients near the inner surface of the plasma membrane (PM). In particular we simulated the refilling of the sarcoplasmic reticulum (SR) via PM-SR junctions during asynchronous [Ca2+]i oscillations in smooth muscle cells of the rabbit inferior vena cava. We have combined confocal microscopy data on the [Ca2+]i oscillatio...

plicing factors, usually associated with RNA polymerase II transcripts, have a temporary home near sites of RNA polymerase I transcription, as shown on page 51 by Bubulya et al. During interphase, premRNA splicing factors such as the serine arginine–rich (SR) proteins reside in nuclear speckles, along with other pre-mRNA processing proteins. The speckles disassemble during mitosis, and then ref...

plicing factors, usually associated with RNA polymerase II transcripts, have a temporary home near sites of RNA polymerase I transcription, as shown on page 51 by Bubulya et al. During interphase, premRNA splicing factors such as the serine arginine–rich (SR) proteins reside in nuclear speckles, along with other pre-mRNA processing proteins. The speckles disassemble during mitosis, and then ref...

OBJECTIVES This study sought to systematically investigate the interactions between the extrinsic and intrinsic cardiac autonomic nervous system (ANS) in modulating electrophysiological properties and atrial fibrillation (AF) initiation. BACKGROUND Systematic ganglionated plexi (GP) ablation to evaluate the extrinsic and intrinsic cardiac ANS relationship has not been detailed. METHODS The ...

plicing factors, usually associated with RNA polymerase II transcripts, have a temporary home near sites of RNA polymerase I transcription, as shown on page 51 by Bubulya et al. During interphase, premRNA splicing factors such as the serine arginine–rich (SR) proteins reside in nuclear speckles, along with other pre-mRNA processing proteins. The speckles disassemble during mitosis, and then ref...