introduction: it is a common protocol to use 201tl for the rest and 99mtc for the stress cardiac spect imaging. theoretically, both types of imaging may be performed simultaneously using different energy windows for each radionuclide. however, a potential limitation is the cross-contamination of scattered photons from 99mtc and collimator x-rays into the 201tl energy window. we used a middle en...

BACKGROUND: This study focuses on quantitative reconstruction of dynamic cardiac SPECT. MATERIAL AND METHODS: The Karhunen-Loeve (KL) transform is first applied to gated frames or sinogram data to de-correlate the dynamic information along the time direction. Then the Poisson noise is treated by a penalized weighted least-squares minimization, followed by an analytical inversion of the treated...

4D computed tomography (4D-CT) is an important modality in medical imaging due to its ability to resolve patient anatomy motion in each respiratory phase. Conventionally 4D-CT is accomplished by performing the reconstruction for each phase independently as in a CT reconstruction problem. We propose a new 4D-CT reconstruction algorithm that explicitly takes into account the temporal regularizati...

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introduction: poor sensitivity and poor signal to noise ratio because of low injected thallium dose and presence of scattered photons are the main problems in using thallium in scintigraphic imaging of the heart. scattered photons are the main cause of degrading the contrast and resolution in spect imaging that result in error in quantification. thallium decay is very complicated and photons ar...