Ageing is a natural process. Discoveries in medical science and improved social conditions during the last few decades have increased the life span of human beings. Essentially geriatrics is concerned with the people aged 65 years and above. The biological changes of ageing are clear but the mechanisms that mediate them are not. Various contradictory theories exist in this regard but there is a...

The antagonistic pleiotropy (AP) theory of ageing predicts genetically based trade-offs between investment in reproduction in early life and survival and performance in later life. Laboratory-based research has shown that such genetic trade-offs exist, but little is currently known about their prevalence in natural populations. We used random regression 'animal model' techniques to test the gen...

Almond seeds age rapidly during storage at high relative humidity (80%) an d moderate temperature (20°C). The content of lipid decreased during accelerated ageing up to 40 d. The levels of linoleic (Cl8:2) and linolenic (Cl8:3) acids in almond lipid fraction also decreased during agei/lg up to 20 d. The aged seeds contain high levels of malondialdehyde, a product of the peroxidatio/l of unsatur...

The main task of this work was to study the influence of the cooling conditions after homogenization of the 6082 aluminium alloys. The effect of the solution heat treatment temperature on the mechanism and ageing kinetics of the two commercial wrought aluminum alloys 6005 and 6082 was also analyzed. The alloys were heat treated—T4 with a wide range of solution heat treatment temperature from 51...

This research was carried out to study the effect of ageing on antioxidant and biochemical changes of wheat (Triticum aestivum L.) seeds. The experiment laid out in completely randomized design (CRD) with four replications in Islamic Azad University, Boroujerd Branch, Boroujerd, Iran in 2015. The seeds of wheat (cv Sardari) were harvested at maturity and ageing treatments were done at 43° C wit...

Chronic kidney disease stage 5 is a global health challenge in the context of population ageing across the world. The range of treatment options available to patients at all ages has increased and includes transplantation and dialysis. However, these options are often seen as inappropriate for older frailer patients who are now offered the option of conservative kidney management, which is pres...

Introduction: The demography of Bulgaria is characterized by a steady trend for a negative natural growth and increase of the relative share of elderly people. This is a challenge to the health and the social systems. Social reports point out: a) unsatisfactory pensions, and b) impoverishment of the group of elderly persons above retirement age. In this context a greater number of people with d...

The molecular mechanisms leading to human senescence are still not known mostly because of the complexity of the process. Different research approaches are used to study ageing including studies of monogenic segmental progeroid syndromes. None of the known progerias represents true precocious ageing. Some of them, including Werner (WS), Bloom (BS), and Rothmund-Thomson syndromes (RTS) as well a...