The aim of this study was to investigate the expression of LRRC4 in nasopharyngeal carcinomas, nasopharyngeal precancerous lesions, and nasopharyngitis as well as the clinical significance of LRRC4. Fifty patients with nasopharyngeal carcinoma were selected as study subjects; 28 patients with chronic nasopharyngitis and 22 patients with nasopharyngeal precancerous lesions served as controls. Im...

Antrochoanal polyp is a benign, solitary polypoid lesion arising from the edematous mucosa of the maxillary sinus and extending through the maxillary ostium into the nose. In children, it constitutes 33% of all nasal polyps. It presents most commonly with unilateral nasal obstruction and purulent rhinorrhea. Surgery is the usual treatment for antrochoanal polyps. The primary aim of treatment fo...

BACKGROUND The aim of this study was to determine the most frequently presenting tumors exclusive to the head and neck within the pediatric population, and to identify racial disparities within the existing incidence rates. MATERIAL/METHODS The population-based Surveillance, Epidemiology, and End Results (SEER) registry was utilized to identify the frequency and incidence rates of various tum...

eratomas are neoplasms derived from germ cells with omponents of the three embryonic layers (ectoderm, mesoerm, and endoderm), that occur in any age group but re more prevalent in childhood, and have no gender reference.1,2 The lesions can be benign (mature, dermoid, nd cystic teratomas) or malignant (immature and solid tertomas), and can affect any structure in the midline).1--3 The linical pr...

Sjögren syndrome (SS) is the second most common autoimmune disease, affecting mainly middle-aged women. The disease might occur alone (primary SS) or in association with other autoimmune diseases such as rheumatoid arthritis (secondary SS). The important symptoms of SS, dry mouth (xerostomia) and dry eyes (keratoconjunctivitis sicca), result from lymphocytic infiltration and destruction of the ...

Juvenile nasopharyngeal angiofibroma is tumour almost exclusively seen in adolescent males, constituting less than 1% of all neoplasms in head and neck. They are benign and locally spreading and are highly vascular in nature and thus prove to be a surgical challenge because of its complex anatomical location. Here, we present a case report of a 18-year-old male presenting with a mass in his lef...

RATIONALE Nasopharyngeal amyloidosis is a benign, slowly progressive disease that is characterized by extracellular eosinophilic deposition. PATIENT CONCERNS We report a rare case of localized nasopharyngeal amyloidosis. DIAGNOSES The initial chief complaint of this patient was frequent epistaxis and right aural fullness. The initial diagnosis was nasopharyngeal tumor. INTERVENTIONS There...

Epstein-Barr Virus (EBV), the first human virus related to oncogenesis, was initially identified in a Burkitt lymphoma cell line in 1964. EBV infects over 90% of the world's population. Most infected people maintain an asymptomatic but persistent EBV infection lifelong. However, in some individuals, EBV infection has been involved in the development of cancer and autoimmune disease. Nowadays, o...

Epstein-Barr virus (EBV) is associated with a wide variety of B-cell-derived lymphoid neoplasms, including Burkitt lymphoma, lymphomas arising in immunocompromised patients (post-transplant and HIV-associated lymphomas), and Hodgkin lymphoma. In addition, EBV has been linked to some T-cell lymphomas (angioimmunoblastic T-cell lymphoma, extranodal nasal-type natural killer/T-cell lymphoma, and o...

Painful ophthalmoplegia can be caused by numerous pathologic conditions such as aneurysm; neoplasms such as chondrosarcoma, lymphoma, and nasopharyngeal carcinoma; diabetes mellitus; infection; and inflammatory disorders such as sarcoidosis and TolosaHunt syndrome (THS). Described by Tolosa in 1954 and Hunt et al in 1961, THS is an idiopathic, selflimited inflammatory disorder characterized by ...