نتایج جستجو برای: nanotherapy

تعداد نتایج: 174  

2016
Carlos Pérez-Medina Dalya Abdel-Atti Jun Tang Yiming Zhao Zahi A. Fayad Jason S. Lewis Willem J. M. Mulder Thomas Reiner

The application of nanoparticle drug formulations, such as nanoliposomal doxorubicin (Doxil), is increasingly integrated in clinical cancer care. Despite nanomedicine's remarkable potential and growth over the last three decades, its clinical benefits for cancer patients vary. Here we report a non-invasive quantitative positron emission tomography (PET) nanoreporter technology that is predictiv...

Journal: :Onco 2021

Objective: The combination of docetaxel (DTX) with Laser-Activated NanoTherapy (LANT), as a treatment for head and neck cancer (HNC), may enhance the therapeutic efficacy lower doses DTX, thereby minimizing effective dosage, side effects times. Material methods: Three HNSCC cell lines, Detroit 562, FaDu, CAL 27, were treated four combinations DTX + LANT to evaluate dose reduction viability. Res...

Journal: :Advanced nanoBiomed research 2022

Tumor resistance to apoptosis and the immunosuppressive tumor microenvironment are two main reasons for poor outcomes of treatment. Pyroptosis is a newly discovered form programmed cell death, featuring surprising proinflammatory activity. Recent evidence shows that pyroptosis leads strong inflammatory responses significant regression, which different from apoptotic death. Strategies based on t...

Journal: :Advanced therapeutics 2022

Using a preclinical in vivo model of arthritis and the gold standard disease-modifying anti-rheumatic drug, methotrexate, pH-responsive phosphorylcholine polymersomes, elicit both anti-inflammatory anti-arthritic therapeutic efficacy, while drastically minimizing off-target toxicity. First, selective accumulation polymersomes within synovium inflamed joints. Second, targeting ability toward act...

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