Tissue engineering aims at resolving problems such as donor shortage and immune rejection faced by transplantation. Scaffolds (artificial extracellular matrices) have critical roles in tissue engineering. Recently, we developed nano-fibrous poly(L-lactic acid) scaffolds under the hypothesis that synthetic nano-fibrous scaffolding, mimicking the structure of natural collagen fibers, could create...

objective: bioactive glass 45s5 is a surface reactive glass-ceramic biomaterial, developed in 1969. bag 45s5 with particle size of 20-60 nm has the ability of bone regeneration, broad spectrum antibacterial effect, repairs and replaces diseased or damaged bone. the aim of this study was to evaluate the antibacterial activity and determine mic and mbc values of nano-bag45s5 on streptococcus muta...

Platelets were coated with 78-nm silica nanoparticles, 45-nm fluorescent nanospheres, or bovine immunoglobulin G (IgG) through layer-by-layer assembly by alternate adsorption with oppositely charged linear polyions. Sequential deposition on platelet surfaces of cationic poly(dimethyldiallylammonium chloride) and anionic poly(styrene sulfonate) was followed by adsorption of nanoparticles or immu...

Abstract The ratio of poly(lactic acid) (PLA), poly(butylene adipate- co -terephthalate) (PBAT), and calcium carbonate (CaCO 3 ) fillers in PLA/PBAT/CaCO composites was set at 90/10/5, 70/30/5, 30/70/5. effect nano- micro-CaCO on the melting crystallization performance investigated by differential scanning calorimetry. PLA related to PBAT ratio, cooling rate, CaCO particle size composites. Nano...

Psoriasis is a topical disease that leads to red and scratchy skin, most commonly on the knees, elbows, trunk scalp. an inflammatory constrains, aloe-vera, natural product, reported have anti-inflammatory properties. Further, Vitamin-E has antioxidant properties it can aid protect against some of oxidative burden occurs with psoriasis. Naturally, vitamin E broad spectrum benefits for health, ha...

Population studies have shown that high red meat intake may increase colorectal cancer risk. Our aim was to examine the effect of different amounts and sources of dietary protein on induction of the promutagenic adduct O(6)-methyl-2-deoxyguanosine (O(6)MeG) in colonocytes, to relate these to markers of large bowel protein fermentation and ascertain whether increasing colonic carbohydrate fermen...

Dual-emitting photonic nano-objects that can sense changes in the environmental pH are designed based on shell-crosslinked micelles assembled from amphiphilic block copolymers and crosslinked with pH-insensitive chromophores. The chromophoric crosslinkers are tetra-functionalized pyrazine molecules that bear a set of terminal aliphatic amine groups and a set of anilino amine groups, which demon...

Electronically conductive and electrochemically active 3D-scaffolds based on electrospun poly(ethylene terephthalate) (PET) nano-fibers are reported. Vapour phase polymerization was employed to achieve an uniform and conformal coating of poly(3,4-ethylenedioxythiophone) doped with tosylate (PEDOT:tosylate) on the nano-fibers. The PEDOT coatings had a large impact on the wettability, turning the...

Oligophenylalanines are soluble in m-cresol, but oligophenylalanyl-tRNAs are not. This differential solubility can be used to assay oligophenylalanines released from tRNA during their synthesis by wheat germ extracts. When poly U is the message, virtually no free product appears. When poly A U (A < U) is used, a considerable amount of oligophenylalanines are released. The fraction of product re...

Thermally responsive Poly(N-isopropylacrylamide) co-allylamine (PNIPAM-co-ALA) nano-gels were synthesised and grafted onto non-woven polypropylene. Silver nitrate was incorporated into the nano-gels in their expanded state and their antimicrobial properties tested. Bacterial growth was measured before and after the Lower Critical Solution Temperature. Below the LCST, bacteria grew, above the LC...