the aim of this study was to investigate the effect of one session of continuous exercise on a treadmill on hsp72 and tac levels of the hippocampus of male wistar rats. for this purpose, 20 male wistar rats (weight 165±1 gr. and age 6 to 8 weeks old) were assigned randomly into four groups: one control group and three acute endurance training groups (groups 1,2 and 3 were killed 30 minutes, 4 h...

background: antioxidants such as α-tocopherol (vitamin e) and β-carotene (vitamin a) play an important role in protective effect of repeated brief periods of ischemia, namely ischemic preconditioning (ipc). values of these antioxidants were investigated and compared after induction of ischemia reperfusion (ir) and kidney ipc in both male and female rats. methods: forty eight wistar rats were di...

introduction: due to the relation between structure and function of renal glomeruli, the study of glomeruli is very important to the understanding of initiation and progression of diabetic glomerulopathy. it seems that glomeruli disappear during the course of diabetic nephropathy without leaving recognizable corpuscles. this study was aimed to show diabetes mellitus effects on changes in renal ...

objective(s):some pathologic situations such as diabetes and metabolic syndrome are associated with alternation in nitric oxide level. incidence of these condition increases with aging. on the other hand, insulin secretion is modulated by nitric oxide, and nitric oxide synthase (nos) activity is also altered in diabetes. in this study, modification in the enzyme activity associated with aging a...

an in vivo experiment was conducted to study the effects of probiotic bacillus coagulans spores, with and without prebiotic, inulin, on gastrointestinal (gi) microbiota of healthy rats and its potentiality to survive in the gi tract. forty-eight male wistar rats were randomly divided into four groups (n=12) and fed as follows: standard diet (control), standard diet supplied with 5% w/w long cha...

objective(s): leptin exerts various effects on appetite and body weight. disruption of the obesitygene is precedent to fatness. insulin or glucose elevates leptin, but streptozotocin reduces it. however, controversial data exist for the effects of leptin on diabetes and leptin level in each gender. leptin can damage the kidney function but little evidence exists for its hepatic effects. the aim...

background and objective: tamoxifen is one of the selective estrogen receptor modulators that exerts estrogen / anti-estrogen effects in various tissues. this study was done to evaluate the effect of chronic administration of tamoxifen on spatial memory and passive avoidance task in adult male wistar rats. methods: in this experimental study, 48 adult male wistar rats were randomly divided into...