نتایج جستجو برای: n8

تعداد نتایج: 384  

Journal: :Proceedings of the Royal Society of Medicine 1939
I Ayesh M D Sanders A I Friedmann

The association of two rare ocular conditions of unknown aetiology presents the clinician with an opportunity to study interrelating factors. The association of retinitis pigmentosa with Coats's disease has been previously reported in three patients (Zamorani, I956; Morgan and Crawford, I968), in all of whom bilateral involvement occurred with severe visual loss. The present case which has been...

Journal: :Chemical communications 2013
Hang Zhao Shiliang He Mingli Yang Xiurong Guo Guang Xin Chaoyang Zhang Ling Ye Liangyin Chu Zhihua Xing Wen Huang Qianming Chen Yang He

We designed and synthesized the Janus-type TA nucleosides (1-3) by using a transglycosylation protocol. Surprisingly, the subtle translocation of the ribose from N8 to N1 by about 230 pm in space leads to the formation of entirely different shaped superstructures, micro-flowers for J-AT and nano-bundles for J-TA.

Journal: :Bratislavske lekarske listy 2013
V Hytych A Taskova P Horazdovsky Z Konopa R Demes J Cermak A Vrabcova P Hoferka R Pohnan

BACKGROUND Constituent part of radical lung resection for lung cancer is a dissection of mediastinal lymph nodes. Lymphadenectomy is a standard procedure in an assessment of clinical stage of the disease. The aim of the study was to map metastasizing of bronchogenic non-small cell lung carcinoma into homolateral mediastinal lymph nodes and to assess the importance of mediastinal lymphadenectomy...

Journal: :Clinical & experimental ophthalmology 2008
Justin C Sherwin Jill E Keeffe Hannah Kuper F M Amirul Islam Andreas Muller Wanjiku Mathenge

BACKGROUND Presbyopia is the most common reason for requiring spectacles in low-income regions, although the unmet need for presbyopic spectacles in these regions is very high. The aim of this study was to estimate the prevalence of presbyopia, and the functional impairment and spectacle use among persons with presbyopia in a rural Kenyan population. METHODS A cross-sectional study was carrie...

Journal: :Earthline Journal of Chemical Sciences 2021

Journal: :Bioorganic & medicinal chemistry letters 2009
Dafydd R Owen John K Walker E Jon Jacobsen John N Freskos Robert O Hughes David L Brown Andrew S Bell David G Brown Christopher Phillips Brent V Mischke John M Molyneaux Yvette M Fobian Steve E Heasley Joseph B Moon William C Stallings D Joseph Rogier David N A Fox Michael J Palmer Tracy Ringer Margarita Rodriquez-Lens Jerry W Cubbage Radhika M Blevis-Bal Alan G Benson Brad A Acker Todd M Maddux Michael B Tollefson Brian R Bond Alan Macinnes Yung Yu

A new class of potent and selective PDE5 inhibitors is disclosed. Guided by X-ray crystallographic data, optimization of an HTS lead led to the discovery of a series of 2-aryl, (N8)-alkyl substituted-6-aminosubstituted pyrido[3,2b]pyrazinones which show potent inhibition of the PDE5 enzyme. Synthetic details and some structure-activity relationships are also presented.

2012
Domenica Veniero Marta Bortoletto Carlo Miniussi

Transcranial magnetic stimulation-electroencephalogram (TMS-EEG) co-registration offers the opportunity to test reactivity of brain areas across distinct conditions through TMS-evoked potentials (TEPs). Several TEPs have been described, their functional meaning being largely unknown. In particular, short-latency potentials peaking at 5 (P5) and 8 (N8) ms after the TMS pulse have been recently d...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده مهندسی 1391

به دلیل محدودیت ها و مشکلات زیست محیطی، استفاده از منابع جدید انرژی به جای منابع فسیلی امری الزامی است. بیودیزل حاصل از ریزجلبک ها، یکی از این نوع انرژی ها است که در سال های اخیر مورد توجه قرار گرفته است. در این مطالعه، شرایط کشت گونه ریزجلبک chlorella vulgaris بطور عملی مورد بررسی قرار گرفت و میزان تولید زیست توده و لیپید سنتز شده آن اندازه گیری و آنالیز گردید. روش های موجود برای تعیین زیست تو...

Journal: :Acta Scientiarum. Biological Sciences 2021

The use of genotypes more adapted to climatic conditions can contribute increase the yield onion producers. goal this study was evaluate agronomic performance 15 in soil and Guarapuava, state Paraná. conducted experimental area Horticulture, Cedeteg campus, Universidade Estadual do Centro-Oeste (UNICENTRO), Paraná, Brazil, from July November 2018. design used randomized blocks, with four replic...

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