Die Bereiche RNA-Modifikation und RNA-Schaden weisen beide eine Vielzahl nicht-kanonischer Nukleosidstrukturen auf. Während sich RNA-Modifikationen zur Verbesserung der RNA-Funktion entwickelt haben, impliziert die Bezeichnung negative Auswirkungen. Auf Grundlage Markierung mit stabilen Isotopen Massenspektrometrie berichten wir von Identifizierung Charakterisierung 2-Methylthio-1,N6-ethenoaden...

The cyclic AMP receptor protein (CRP) from Mycobacterium tuberculosis is a cAMPresponsive global transcriptional regulator, responsible for the regulation of a multitude of diverse proteins. We have determined the crystal structures of the CRP-cAMP and CRPN6-cAMP derivative bound forms of the enzyme to 2.2 and 2.3 Å resolution, respectively, in order to investigate cAMP mediated conformational ...

Five new NNN pincer-type ligands and their palladium complexes were successfully synthesised characterised by FT-IR, 1H NMR, 13C UV–vis analyses. TEM analysis was used to observe the morphological character of black residues obtained from fourth cycle reusability test. Furthermore, suitable crystals N2,N6-bis(2-tert-butylphenyl)pyridine-2,6-dicarboxamide its complex elucidated with X-ray single...

Sažetak Cilj ovog istraživanja bio je analizirati udio masti i sastav masnih kiselina u uzorcima M. biceps femoris istarskog i dalmatinskog pršuta. Analiziran je sadržaj zasićenih (SFA), mononezasićeniih (MUFA) i polinezasićenih (PUFA) masnih kiselina. Udio masti u istarskom pršutu bio je 7,45-21,12%, dok u dalmatinskom 9,49-21,29%. Sastav masnih kiselina istarskog i dalmatinskog pršuta nije se...

The role of urease in Helicobacter pylori adherence to and internalization by Kato III cells was investigated. Kato III cells were incubated with wild-type strains (N6 or P1), with isogenic mutants lacking urease (N6ureB::TnKm or P1ureA::TnMax5) or producing the inactive apoprotein (N6ureG::TnKm), and with urease-positive clones recovered after complementation of N6ureB::TnKm with ureAB. Bacter...

The efficiency of maize transformation mediated by Agrobacterium tumefaciens is influenced by various factors. The aim of this study was to test the effect of different concentrations of N6 salts (50% – half strength, and 100% full strength) in the infection and cocultivation media on genetic transformation efficiency of the L3 tropical elite maize line. Immature embryos were transformed via A....

BACKGROUND Ribosomal RNAs contain many modified nucleotides. The functions of these nucleotides are poorly understood and few of them are strongly conserved. The final stem loop in 16S-like rRNAs is an exception in both regards. In both prokaryotes and eukaryotes, the tetranucleotide loop that caps the 3'-terminal stem contains two N6, N6-dimethyladenosine residues. The sequence and pattern of ...

Inert and optically active pseudo-octahedral Cr(III)N6 and Ru(II)N6 chromophores have been incorporated by self-assembly into heterobimetallic triple-stranded helicates HHH-[CrLnL3]6+ and HHH-[RuLnL3]5+. The crystal structures of [CrLnL(3)](CF(3)SO(3))(6) (Ln=Nd, Eu, Yb, Lu) and [RuLnL3](CF3SO3)5 (Ln=Eu, Lu) demonstrate that the helical structure can accommodate metal ions of different sizes, w...