Murine blood plasma rapidly inactivates nitrosamides and nitrosocarbamates but not nitrosoureas. The mechanism of this inactivation in murine blood plasma has been investigated. The vast majority of activity (>97%) was inhibited by serine hydroxylase inhibitors. Also, 92% of the activity was inhibited by bis(pnitrophenyl)phosphate, a selective inhibitor of carboxy(esterases. Decomposition produ...
