Several studies have shown that the carcinogen N-acetoxy-N-2-acetylaminofluorene (AAAF) reacts in vivo and in vitro with native DNA and that the DNA contains a major (80%) adduct N(deoxyguanosin8-yl)-acetylaminofluorene (dGuo8-AAF) and a minor (20%) adduct 3{deoxyguanosin-N2-yl)-acetylaminofluorene (dGuo-N2-AAF) (reviewed [1,2]). It has been shown that the major alteration induced by the fluore...

A bstract In holographic duality, boundary states that have semiclassical bulk duals must obey inequalities, which bound their subsystems’ von Neumann entropies. Hitherto known inequalities constrain entropies of reduced on up to N = 5 disjoint subsystems. Here we report one new such inequality, involves 7 regions. Our work supports a recent conjecture the structure predicted existence and sche...

Background: New amino derivatives of NBD type are high interest due to their strong fluorescence, while compounds containing a disulphide moiety in nano-chemistry easiness attaching noble nanoparticles. Therefore, this work new fluorescent derivative and cystamine was obtained. Methods: The reaction between NBD-chloride occurs straightforwardly, the isolated compound characterized by IR, UV-Vis...

refractory celiac disease (rcd) is when malabsorption symptoms and villous atrophy persist despite strict adherence to a gluten free diet (gfd) for more than 12 months and other causes of villous atrophy have been ruled out.  rcd is considered a rare disease and almost exclusively occurs in adults. persistent diarrhea, abdominal pain, weight loss are the most common symptoms in rcd. also, anemi...

The synthesis of 3-morpholino-7-[N-methyl-N-(4′-carboxyphenyl)amino]phenothiazinium chloride is reported here. Interestingly, non-symmetric phenothiazinium salt functionalized with a carboxylic acid group that allows the easy and stable anchoring on metal oxides. In addition, morpholine unit reduces dye aggregation tendency; thus, improving its potential applications in biomedical photo-electro...