Our previous results from a limited number of cell lines have sug gested that the bis(ethyl)polyamine analogues exert a phenotype-specific response in human lung cancer cells. In the present study, we have extended this work to analyze the response of the 4 major forms of human lung cancer to the polyamine analogue JV-W2-bis(ethyl)spermine (BESpm). The results suggest that non-small cell phenot...