The indoor mycotoxins inhalation exposure of patients (n=25) was studied using a highvolume air sampler (60 cfm x 24 h) with a micropore-paper filter (8x11 inches). The filters were evaluated for cytotoxicity caused by mycotoxins using the MTT-cell culture bioassay and by culture identification. A subset of samples was analyzed with an enzyme-immuno assay for occurrence of macrocyclic trichothe...

Lon W. Whitlow Department of Animal Science North Carolina State University Raleigh, NC 27695 Phone: 919-515-7602 Fax: 919-515-2152 Email: [email protected] Summary Considerable research has been directed at finding methods to prevent toxicity of mycotoxins. Some of the approaches have included mycotoxin separation from contaminated feeds, detoxification and inactivation. Detoxification and ...

Mycotoxins are secondary metabolites of several species of fungi. The health implications o f mycotoxins are far reaching, ranging from induction of emesis in livestock to warranting classification as a known human carcinogen by the U.S. Environmental Protection Agency (USEPA). There exists inherent difficulty in analyzing several mycotoxins simultaneously due to differences in chemical structu...

Mycotoxins are one of the main factors impacting food safety. Mycotoxin contamination has threatened the health of humans and animals. Conventional methods for the detection of mycotoxins are gas chromatography (GC) or liquid chromatography (LC) coupled with mass spectrometry (MS), or enzyme-linked immunosorbent assay (ELISA). However, all these methods are time-consuming, require large-scale i...

The contamination of foods and feeds is a significant problem in worldwide. Mycotoxins are secondary metabolites of fungi, particularly by many species of Aspergillus, Fusarium, Penicillium, Claviceps and Alternaria in many agricultural crops, especially in cereals and most oilseeds. Aflatoxins, ochratoxins, trichothecenes, zearelenone and fumonisins are the mycotoxins of greatest agro-economic...

Molds are filamentous (fuzzy or dusty looking) fungi that occur in many feedstuffs including roughages and concentrates. Molds can infect dairy cattle, especially during stressful periods when they are immune suppressed, causing a disease referred to as a mycosis. Molds also produce poisons called mycotoxins that affect animals when they consume mycotoxin contaminated feeds. This disorder is ca...

Molds are filamentous (fuzzy or dusty looking) fungi that occur in many feedstuffs including roughages and concentrates. Molds can infect dairy cattle, especially during stressful periods when they are immune suppressed, causing a disease referred to as mycosis. Molds also produce poisons called mycotoxins that affect animals when they consume mycotoxin contaminated feeds. This disorder is call...

Mycotoxins severely threaten the health of humans and animals. For this reason, many countries have enforced regulations and recommendations to reduce the dietary exposure. However, even though regulatory actions must be based on solid scientific knowledge, many aspects of their toxicological activity are still poorly understood. In particular, deepening knowledge on the primal molecular events...

Mycotoxins are secondary metabolites of fungi that grow on a variety of grains, feedstuffs and animal feed. Feed containing moderate to high levels of mycotoxins cause clinical symptoms in most animals, ranging from organ damage to acute mortality. Consumption of low levels of contaminated feed may result in subclinical problems such as immunosuppression. More than 500 mycotoxins have been iden...