A new and general procedure is described for a detailed analysis of time-resolved fluorescence depolarisation data in the presence of electronic energy migration. An isotropic ensemble of bifluorophoric molecules (D(1)-R-D(2)) has been studied to demonstrate its utility. Intramolecular donor-donor energy migration occurs between the two donor groups (D), which are covalently connected to a rigi...

Leukocytes recruitment to thrombi supports an intimate cellular interaction leading to the enhancement of pro-coagulant functions and pro-inflammatory responses at site of vascular injury. Recent observations of neutrophil extracellular traps (NETs) formation and its mutual reactions with platelet thrombi adds more clinical interest to the growing body of knowledge in the field of platelet-leuk...

This paper addresses the issue of performing global sensitivity analysis of model output with dependent inputs. First, we define variance-based sensitivity indices that allow for distinguishing the independent contributions of the inputs to the response variance from their mutual dependent contributions. Then, two sampling strategies are proposed for their non-parametric, numerical estimation. ...

Desert locusts, Schistocerca gregaria, show extreme phenotypic plasticity, transforming between a little-seen solitarious phase and the notorious swarming gregarious phase depending on population density. An essential tipping point in the process of swarm formation is the initial switch from strong mutual aversion in solitarious locusts to coherent group formation and greater activity in gregar...

Missing teeth should be replaced as soon as possible to maintain arch integrity and thereby avoid both morphologic and functional derangements in the occlusion. Otherwise, changes occur that upset the masticatory system, such as extrusion of the teeth opposing the edentulous areas along with their alveolar housing, their supporting tissues and ultimately the maxillary sinus. Concurrently with e...

EGF receptor (EGFR) and c-Src are the prototypes that individually represent the receptor and nonreceptor tyrosine kinases respectively. Accumulated evidence reveals the association between EGF-activated EGFR and c-Src that leads to activation of both kinases. Importantly, their mutual interaction is required for many EGFR-mediated cellular functions including proliferation, migration, survival...

Among all measures of independence between random variables, mutual information is the only one that is based on information theory. Mutual information takes into account of all kinds of dependencies between variables, i.e., both the linear and non-linear dependencies. In this paper we have classified some well-known bivariate distributions into two classes of distributions based on their mutua...