Intact soleus and extensor digitorum longus muscles in the rat were freely grafted to the contralateral leg after either no preliminary treatment or 14 days prior denervation. Normal muscle grafts during the first week were characterized by a central zone of degenerating original muscle fibers (disappearing by 7-9 days) and a peripheral zone, containing regenerating muscle as well as small numb...

It has been established that the extraocular muscles of several mammalian species possess two different types of muscle fibers, twitch and slow fibers, with distinct differences in their respective fine structures (1-8). In this investigation we have examined the fine structure of isolated and identified extraocular muscle fibers in rabbit. Though there has been general agreement on the differe...

From the histochemical study of the intercostal muscles of cat, the following results were obtained. 1. Three different types of muscle fibers have been clearly distinguished in intercostal muscles by histochemical demonstration of succinic dehydrogenase; namely, the white fibers are stained faintly, while the red fibers deep blue and the intermediate fibers purple or bluish purple. 2. The diff...

In most groups of electric fish, the electric organ (EO) derives from striated muscle cells that suppress many muscle phenotypic properties. This phenotypic conversion is recapitulated during regeneration of the tail in the weakly electric fish Sternopygus macrurus. Mature electrocytes, the cells of the electric organ, are considerably larger than the muscle fibers from which they derive, and i...

PURPOSE To investigate the distribution of the intermediate filament (IF) proteins desmin, vimentin, and nestin in human extraocular muscles (EOMs). METHODS Healthy adult EOM samples were serially sectioned (5 and 1 μm) and processed for immunohistochemistry, with specific antibodies (Abs) against desmin, vimentin, and nestin and different myosin heavy chains (MyHCs), including the newly char...

Effects of mechanical over-loading on the characteristics of regenerating or normal soleus muscle fibers were studied in dystrophin-deficient (mdx) and wild type (WT) mice. Damage was also induced in WT mice by injection of cardiotoxin (CTX) into soleus muscle. Over-loading was applied for 14 days to the left soleus muscle in mdx and intact and CTX-injected WT mouse muscles by ablation of the d...

The degree of minced rat muscle regeneration in the absence of nerve fibers was compared with that of normal regenerates between one and 270 days postoperatively. Up to around 30 days, the number of muscle fibers and their morphology were comparable in both normal innervated and denervated regenerates; both showed clear cross striations and peripherally located nuclei. Histochemically, SDH and ...

It has been established that the extraocular muscles of several mammalian species possess two different types of muscle fibers, twitch and slow fibers, with distinct differences in their respective fine structures (1-8). In this investigation we have examined the fine structure of isolated and identified extraocular muscle fibers in rabbit. Though there has been general agreement on the differe...

In this study, the deformation of different fibers of the rat m. plantaris during "isometric" contractions at different muscle lengths was considered. Because the m. plantaris has an obviously inhomogeneous architecture, its fibers on the medial side of the muscle belly are judged to be shorter than those on the lateral side of it. It was expected that longitudinal deformation of different fibe...

Specific antisera were raised in rabbits against column-purified myosins from a slow avian muscle, the chicken anterior latissimus dorsi (ALD), and a slow-twitch mammalian muscle, the guinea pig soleus (SOL). The antisera were labeled with fluorescein and applied to sections of muscles from various vertebrae species. Two distinct categories of the slow fibers were identified on the basis of the...