INTRODUCTION Sleep problems, including insomnia, apnea, and restless legs syndrome, are common, burdensome, and under-recognized in the United States. We sought to examine the association of sleep problems with diabetes among community-dwelling US adults. METHODS We examined self-reported sleep problems in 9,848 adults (aged ≥20 y) participating in the National Health and Nutrition Examinatio...

Chronic intermittent hypoxia occurring in obstructive sleep apnea (OSA) is independently associated with nonalcoholic fatty liver disease (NAFLD). pulmonary (COPD) has also been suggested to be linked disease. In this individual participant data meta-analysis, we investigated the association between damage and OSA COPD severity. Patients suspected of underwent polysomnography (PSG) or home test...

OBJECTIVE Sleep apnea (SA) has been linked with various forms of cardiovascular disease, but little is known about its association with peripheral artery disease (PAD) measured using the ankle-brachial index. This relationship was evaluated in the Hispanic Community Health Study/Study of Latinos. APPROACH AND RESULTS We studied 8367 Hispanic Community Health Study/Study of Latinos participant...

Obese subjects have a high prevalence of left ventricular (LV) hypertrophy. It is unclear to what extent LV hypertrophy results directly from obesity or from associated conditions, such as hypertension, impaired glucose homeostasis, or obstructive sleep apnea. We tested the hypothesis that LV hypertrophy in severe obesity is associated with additive effects from each of the major comorbidities....

BACKGROUND While obstructive sleep apnea syndrome is defined by both polysomnographic (PSG) abnormalities and symptoms, severity is quantified primarily by the apnea-hypopnea index (AHI) alone. OBJECTIVE To determine the correlation between standard PSG indices (AHI and others) and self-reported sleepiness, mental health status, and general health in patients with sleep apnea. DESIGN Cross-...

OBJECTIVE To determine the longitudinal associations between obstructive sleep apnea, carotid artery intima-media thickness (IMT), and plaque. APPROACH AND RESULTS This is a population-based, prospective cohort study conducted from July, 1989, to November, 2012, on 790 randomly selected Wisconsin residents who completed a mean of 3.5 (range, 1-6) polysomnograms during the study period. Obstru...

OBJECTIVE To examine whether circulating leptin levels correlate with the severity of disease in patients with obstructive sleep apnea. DESIGN Prospective nonrandomized study. SETTING Referral sleep laboratory for patients with sleep-disordered breathing and biochemistry laboratory. Patients Thirty-two subjects (mean +/- SD age, 47 +/- 12 years) who were referred for suspected sleep apnea u...

introduction:the overlap syndrome, consisting ofobstructive sleep apnea hypopnea syndrome (osahs) and chronic obstructvie pulmonary disease (copd) is a major problem in copd patients. oshas corresponds to the likelihood of systemic hypertension.the present study was aimed to evaluate the association between apnea-hypopnea index and diastolic blood presssure (dbp) in overlap  patients. materials...

STUDY OBJECTIVE To evaluate the tolerability and to find predictors of treatment success for an individually adjusted, one-piece mandibular advancement device in patients with snoring and obstructive sleep apnea. DESIGN Prospective study. SETTING Departments of Respiratory Medicine and Orthodontics, Umeå University. PATIENTS Six hundred nineteen of 630 patients (98%), who consecutively re...