Introduction: Interferon beta is one of the members of type I interferons. Creating R27T and V101F mutations is one of the important researches performed to improve function, decrease immunogenicity, increase expression and increase half-life of interferon beta. In this study, the effects of R27T and V101F mutations on interferon beta binding to interferon receptors were studied by molecular do...

this paper deals with the problem of user-server assignment in online social network systems. online social network applications such as facebook, twitter, or instagram are built on an infrastructure of servers that enables them to communicate with each other. a key factor that determines the facility of communication between the users and the servers is the expected transmission time (ett). a ...

the probability of losing a customer in m/g/n/0 and gi/m/n/0 loss queuing systems withheterogeneous servers is minimized. the first system uses a queue discipline in which a customer who arriveswhen there are free servers chooses any one of them with equal probability, but is lost otherwise. providedthat the sum of the servers rates are fixed, loss probability in this system attains minimum val...