Anti mullerian hormone (AMH) is a homodimeric glycoprotein belonging to the transforming growth factors (TGF-β) super family. AMH plays a fundamental role in the regression of mullerian ducts in male embryo. In boys, it is significantly produced in Sertoli cells of testes until puberty and then slowly decreases to residual values for the rest of the men’s life. In female, it is secreted by gran...

ii To my family and friends who supported me throughout this journey iii ACKNOWLEDGMENTS This project would not have been possible without Drs. Donna and Mark Santillan. I would like to thank them both for their endless support and advice in the development of this program. Thanks to Dr. Kristi Borowski for allowing us access to her serum tissue bank and birth certificate data, and to Dr. Ben L...

background: this study aimed to evaluate the strength of anti?mullerian hormone (amh) and follicle stimulating hormone (fsh) in reflecting the antral follicle count (afc) in infertile females. materials and methods: this cross?sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. serum samples collected on the 3rd day of the cycle were assayed for ...

Mullerian inhibiting substance (MIS) is the gonadal hormone that causes regression of the Mullerian ducts, the anlagen of the female internal reproductive structures, during male embryogenesis. MIS is a member of the large transforming growth factor-beta (TGF beta) multigene family of glycoproteins that are involved in the regulation of growth and differentiation. The proteins in this gene fami...

As the chronological age increases, there is a physiological decline in reproductive potential of women. Moreover, the chronological age of women may not reflect the biological age of her ovaries. Various endocrine markers have been used to assess the ovarian reserve. The changing pattern of the endocrine markers; follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2) and ...

Background Anti-Müllerian hormone (AMH) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. Abnormal levels of AMH and follicle stimulating hormone (FSH) may indicate a woman’s diminished ability or inability to conceive. Our aim is to investigate the changes in serum AMH and FSH concentrations at different age groups and its correlation w...