Mucormycosis are a group of invasive infections caused by filamentous fungi of the Mucoraceae family. Mucormycosis is essentially limited to immunocompromised patients with poorly controlled diabetes mellitus, hematologic malignancy, organ transplant, chemotherapy, chronic renal insufficiency, malnutrition, deferoxamine therapy and severe burns. The fungi invade arteries leading to thrombosis t...

We report three cases of ileocolic mucormycosis in adult immunocompromised patients presenting as acute abdomen. All patients underwent laparotomy but two of them died from multiorgan failure before the diagnoses were confirmed. The diagnosis of gastrointestinal mucormycosis is rarely suspected, and antemortem diagnosis is made in only 25%-50% of cases. These cases illustrate the difficulty enc...

Rhino-orbitocerebral mucormycosis is the most common form of central nervous system (CNS) infection with mucormycosis. It is a rare but life-threatening infection. Isolated cerebral infection with mucormycosis without any rhino-orbital focus is extremely rare. Isolated cerebral mucormycosis is common in intravenous (IV) drug abusers and immunocompromised patients. Diabetes, long-term steroid us...

Mucormycosis (zygomycosis) is an acute and often fatal opportunistic fungal infection. Predisposing factors in the development of mucormycosis are nonspecific and include hyperglycemia, hematologic malignancies, neutropenia, pharmacologic immunosuppression, solid organ or bone marrow/stem cell transplantation, burns, trauma, malnutrition, and intravenous drug use. Mucormycosis has also been des...

mucormycosis is a serious fungal infection caused by the filamentous fungi of the mucorales order of the class of zygomycetes. mucormycosis is classically defined as an opportunistic fatal infection. in this report we explain a 49 years old woman with palato-orbital tract as a sequel of rhino cerebral mucormycosis and end stage renal disease candidate for kidney transplantation. difficulties in...

In recent years, substantial advances have been achieved in the treatment of mucormycosis. It is now clear that early initiation of therapy results in substantially better outcomes, underscoring the need to maintain a high index of suspicion and aggressively biopsy potential lesions. Increasing data support the need for surgical excision of infected and/or necrosed tissue whenever feasible. Bas...

Mucormycosis is an emerging angioinvasive infection caused by the ubiquitous filamentous fungi of the Mucorales order of the class of Zygomycetes. Mucormycosis has emerged as the third most common invasive mycosis in order of importance after candidiasis and aspergillosis in patients with hematological and allogeneic stem cell transplantation. Mucormycosis also remains a threat in patients with...

Mucormycosis is a clinical entity attributed to opportunistic fungal infection of order Mucorales. This includes several pathogenic subtypes. It commonly affects the rhinocerebral sites and the immunocompromized patients with devastating results. Visceral mucormycosis is a relatively rare complication. We report the first free sigmoid colon perforation secondary to invasive mucormycosis and dis...

1 Murphy JD, Bornstein S: Mucormycosis of the lung. Ann Intern Med 33:442, 1950 2 Blaknberg HW, Verhoeff D: Mucormycosis of the lung. Ann Rev Resp Dis 79:357, 1959 3 Dillion ML, Sealy WC, Fetter BF: Mucormycosis of the bronchus successfully treated by lobectomy. J Thorac Cardiovasc Surg 35:464, 1958 4 Dillon ML, Sealy WC: Surgical aspects of opportunistic fungus infections. Lab Invest 11 : 1231...

Mucormycosis is a rare complication of immunosuppression. Most of the reported cases have been rhinocerebral or disseminated. Isolated renal involvement is extremely rare and until now less than 30 patients have been reported in the English literature. Isolated renal mucormycosis with renal artery rupture in a liver transplant patient has not been reported so far. Herein we report an extremely ...