metabolic syndrome (ms) is a condition, which constitutes a group of risk factors that occur together and increase the risk for coronary artery disease, stroke and type 2 diabetes mellitus. this disorder is found prevalent in the industrialized societies of the world in epidemic proportions. periodontitis is an oral disease of microbial origin characterized by loss of attachment apparatus of to...

objective: acceptance and commitment therapy is a third generation behavioral therapy that uses mindfulness skills, acceptance and cognitive defusion in order to achieve psychological flexibility. the main purpose of this research was to evaluate the effectiveness of acceptance and commitment therapy on anxiety in patients with multiple sclerosis( ms). method: this research was carried out base...

abstract background and objective : psychological aspects of chronic diseases has attracted many professionals. because the incidence of sudden and uncontrollable symptoms of many diseases, causing stress and create a variety of negative emotions and mood in patients'. the purpose of this study was to investigate the effectiveness of group reality therapy in reduceing stress, anxiety and depres...

In order to extend our studies designed to elucidate the mechanism of action of intravenous methylprednisolone (ivMP) in symptomatic therapy of relapses in multiple sclerosis (MS) victims, we have evaluated the expression of chemokines: macrophage inflammatory protein 3alpha (MIP-3alpha) and B-lymphocyte chemoattractant (CXCL13) before and after treatment. The data from further exploration of t...

Multiple sclerosis (MS) is an inflammatory autoimmune disease characterized by imbalanced immune regulatory networks, and MS patient-derived T effector cells are inefficiently suppressed through regulatory T cells (Treg), a phenomenon known as Treg resistance. In the current study we investigated T cell function in MS patients before and after interferon-beta therapy. We compared cytokine profi...

Interferon-gamma is produced by immune cells before MS exacerbations, and exogenous IFN-gamma treatment causes MS attacks. IFN-beta production, conversely, rises after exacerbations. IFN-beta therapy ameliorates MS, possibly by lowering IFN-gamma secretion and inhibiting responses to IFN-gamma. IFN-gamma effects are regulated by IFN-gamma receptor (IFNGR) expression. IFN-gamma is pro-inflammato...