objective(s): human and animal studies have shown a close relationship between obesity and asthma severity. here, we examined the effects of diet-induced obesity (dio) on the expression levels of il-1β, irak-1 and traf-6 mrna in male wistar rats tracheal after sensitization with ovalbumin (ova). materials and methods:twenty male wistar rats divided to four groups, included, control group with n...

epidemiological and clinical studies indicate a close relationship between obesity and asthma. here, we determined the impact of diet-induced obesity on the expression levels of il-1β, irak-1 and traf-6 mrna as well as il-1β protein level and pathological changes in male wistar rat’s lung after sensitization with ovalbumin (ova). twenty male wistar rats divided into four groups, control with no...

Introduction: Regulators of G-protein signaling protein negatively control G protein -coupled receptor signaling duration by accelerating Gα subunit guanosine triphosphate hydrolysis. Since regulator of G-protein signaling4 has an important role in modulating morphine effects at the cellular level and the exact mechanism(s) of adrenalectomy-induced morphine sensitization have not been fully cl...

Background: It has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. Morus alba leaf extract (MAE) has hypoglycemic and antioxidant properties. We, therefore, explored the impact of the administration of MAE on steroidogenesis in diabetic rats. Methods: To address this hypothesis, we measured the serum level of glucose, insulin, and f...

introduction: regulators of g-protein signaling protein negatively control g protein -coupled receptor signaling duration by accelerating gα subunit guanosine triphosphate hydrolysis. since regulator of g-protein signaling4 has an important role in modulating morphine effects at the cellular level and the exact mechanism(s) of adrenalectomy-induced morphine sensitization have not been fully cla...