MAP kinase (MPK) cascades in Arabidopsis thaliana and other vascular plants are activated by developmental cues, abiotic stress, and pathogen infection. Much less is known of MPK functions in nonvascular land plants such as the moss Physcomitrella patens Here, we provide evidence for a signaling pathway in P. patens required for immunity triggered by pathogen associated molecular patterns (PAMP...

A mechanistic model of amyloid beta production, degradation, and distribution was constructed for mouse, monkey, and human, calibrated and externally verified across multiple datasets. Simulations of single-dose avagacestat treatment demonstrate that the Aβ42 brain inhibition may exceed that in cerebrospinal fluid (CSF). The dose that achieves 50% CSF Aβ40 inhibition for humans (both healthy an...

Ž . The motion planning kernel MPK is a software system designed to facilitate development, testing, and comparison of robotic and geometric reasoning algorithms. Examples of such algorithms include automatic path planning, grasping, etc. The system has been designed to be open and extensible, so that new methods can be easily added and compared on the same platform. 2001 John Wiley & Sons, Inc.

In federal states, intergovernmental councils were the main institutions through which government and constituent units coordinated their responses to COVID-19. To examine whether peak assumed a leading role during COVID-19 pandemic ensure cross-sectoral as well coordination, this article compares of two “peak councils”—the Conference Premiers (MPK) in Germany Cantonal Governments (KdK) Switzer...

Probiotics are viable microorganisms that are increasingly used for treatment of a variety of diseases. Occasionally, however, probiotics may have adverse clinical effects, including septicemia. Here we examined the role of the intestinal microbiota and the adaptive immune system in preventing translocation of probiotics (e.g., Escherichia coli Nissle). We challenged C57BL/6J mice raised under ...

BACKGROUND The effectiveness of microprocessor-controlled prosthetic knee joints (MPKs) has been assessed using a variety of outcome measures in a variety of health and health-related domains. However, if the patient is to receive a prosthetic knee joint that enables him to function optimally in daily life, it is vital that the clinician has adequate information about the effects of that partic...

Standard methods used in the encryption and decryption process are implemented to protect confidential data. These require many arithmetic logical operations that negatively affect performance of process. In addition, they use private keys a specific length, addition fixed length data block encryption, which may provide possibility penetration these methods, thus decreasing level security. this...

The Loanable funds theory Hypotheses: Individuals care only about real variables (output gains or losses, purchasing-power gains or losses). The marginal productivity of capital assets (MPK) is given and determined by the technical characteristics of the productive assets. It represents the gain, in terms of output, obtained by increasing the capacity of production by one additional capital ass...