In order to be successful, enterprises have to adapt quickly to new opportunities and threats. They have to take smart decisions and execute fast. Innovation and agility become main success factors. The Management of Process Excellence (MPE) is a key enabler. It leads to a functioning “real-time enterprise”. MPE links enterprise strategy with people and technology for the highest operational pe...

Malignant pleural effusion (MPE) is a major problem associated with advanced non-small cell lung cancer for which an optimum treatment strategy has yet to be determined. Notably, vascular endothelial growth factor (VEGF) signaling has been found to influence MPE, and bevacizumab, a VEGF ligand inhibitor, can effectively control MPE. Ramucirumab, a human monoclonal antibody specific for VEGF rec...

The Mobile Payload Element (MPE) is designed to be a small, autonomous and innovative rover of ~15kg for planetary exploration. Its novel capability is to acquire clearly documented samples from surface as well as subsurface locations, and to bring them back to its lander for further analyses. Although the ESA Lunar Lander served as reference scenario for the MPE development, it is compatible t...

Given a belief network with evidence, the task of finding the l most probable ex­ planations (MPE) in the belief network is that of identifying and ordering the l most probable instantiations of the non-evidence nodes of the belief network. Although many approaches have been proposed for solving this problem, most work only for restricted topologies (i.e., singly connected belief net­ works). I...

In addition to computing the posterior distributions for hidden variables in Bayesian networks, one other important inference task is to find the most probable explanation (MPE). MPE provides the most likely configurations to explain away the evidence and helps to manage hypotheses for decision making. In recent years, researchers have proposed a few methods to find the MPE for discrete Bayesia...

BACKGROUND We investigated the association between oxcarbazepine (OXC)-induced maculopapular eruption (MPE) and HLA-B alleles in a northern Han Chinese population, and conducted an analysis of clinical risk factors for OXC-MPE. METHODS Forty-two northern Han Chinese patients who had been treated with OXC in Changchun, China were genotyped. Among them were 14 cases with OXC-induced MPE; the re...

BACKGROUND Long-term outcomes of minor papilla endotherapy (MPE) in pancreas divisum are limited. OBJECTIVE To determine the efficacy of MPE in symptomatic pancreas divisum subgroups. DESIGN This was a retrospective study of patients from an endoscopy database. The data collection instrument included preprocedure and postprocedure pain score, narcotic use, acute pancreatitis episodes, emerg...

Methidiumpropyl-EDTA . iron(II) [MPE . Fe (II)] cleaves double-helical DNA with considerably lower sequence specificity than micrococcal nuclease. Moreover, digestions with MPE . Fe(II) can be performed in the presence of certain metal chelators, which will minimize the action of many endogenous nucleases. Because of these properties MPE . Fe(II) would appear to be a superior tool for probing c...

Background: Malignant pleural effusion (MPE) comes generally with high mortality and poor prognosis. Recurrence of symptomatic MPE is always accompanied by survival quality. In lung adenocarcinoma, researchers speculate whether patients actionable mutation or without are applicable to different management models for MPE. Under the background probability encouraging therapeutic response in Asian...

Estrogens and estrogen metabolites have important functions in cardiovascular and other physiology, yet the patterns of estrogen synthesis, metabolism, and the individual plasma profile of estrogens and estrogen metabolites during human pregnancy as well as in preeclampsia remain undetermined. We performed liquid chromatography mass spectrometry on plasma samples from normotensive pregnant wome...