conclusions the present investigation supports the use of the methanolic extract of a. maurorum as an antiviral drug in folk and modern medicine. this activity may justify its use as a source of natural compounds to control fmdv in infected animals. background foot and mouth disease (fmd) is an infectious disease of cloven-hoofed animals that has adverse economic impacts. given the prevalence o...

since, the most susceptible laboratory animal to foot–and–mouth disease virus (fmdv) is guinea pig, and then one milliliter of fmdv type (o) concentrations of 106-106.5 tcid50was inoculated intradermally (id) to 10 plantar surface of guinea pig (right side). guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

foot-and-mouth disease is an important viral disease of cloven-hoofed animals. inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. the choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. montanide isa 61 vg is a new ready-to-use mineral oil-based adjuvant developed by seppic inc....

results the pellet of the 146s antigen of fmd virus serotype a was developed at a concentration of sucrose 50%. absorbance rate of the foot-and-mouth disease virus serotypes a at wavelengths of 240, 259 and 280 nm was 1.238, 1.573 and 1.157, respectively. moreover, the amount of 146s antigen at the same wavelengths was 163.416, 207.636 and 152.724 μg/ml, respectively. the amount of purified pro...

introduction: foot-and-mouth disease (fmd) is a highly contagious and economically devastating viral disease of livestock that is categorized in list a of animal diseases by the world organisation for animal health (oie). vaccination is effective against fmd and the vaccine production centers largely use the industrial ultra-filtration and chromatography in order to remove the cellular proteins...

Foot-and-mouth disease (FMD) is a major infectious disease in livestock. The common clinical signs in cattle include epidermal vesicles that are majorly distributed around oronasal cavity, feet and teats. The aim of this report is to document an uncommon clinical form of the disease which comprises the occurrence of classic vesicular lesion in a rarely observed location of the horn vegetative t...