The discovery of the antifertility activity of gossypol led scientists and researchers to the development of compounds with antifertility activity that can be used as male contraceptives. These studies resulted in discovery of the antifertility activity of several classes of compounds which have been reported in the literature. This article deals with the synthesis of four new analogues of pyri...

Cerebral language lateralization can be assessed in several ways. In healthy subjects, functional MRI (fMRI) during performance of a language task has evolved to be the most frequently applied method. Functional transcranial Doppler (fTCD) may provide a valid alternative, but has been used rarely. Both techniques have their own strengths and weaknesses and as a result may be applied in differen...

BACKGROUND There are reports showing that l-carnitine alone or in combination with other micronutrients improve sperm parameters. However, comparative studies are still lacking. This study was carried out to compare the short term effects of a combination of eight micronutrients including l-carnitine vs. a mono-substance (l-carnitine alone) on sperm parameters. METHODS This was a prospective,...

This paper compares the Portuguese and Bulgarian consumer price indices (CPI) and attempts to identify some areas in which the CPI compilation methodology could be improved in the two countries. This work is organised into six sections. The first section briefly describes the organisational structure on which the production of the CPI is based in the two countries. The second section focuses on...

Transcutaneous intraluminal impedance measurement (TIIM) is a new method to cutaneously measure gastric contractions by assessing the attenuation dynamics of a small oscillating voltage emitted by a battery-powered ingestible capsule retained in the stomach. In the present study, we investigated whether TIIM can reliably assess gastric motility in acute canine models. Methods. Eight mongrel dog...

This study examined the hypothesis that 5HT3 mechanisms mediate the postprandial gastrocolonic response in humans. Fasting and postprandial colonic tone and motility were studied in 12 healthy volunteers and the effects of a selective 5HT3 antagonist, ondansetron assessed in a double blind, randomised, placebo controlled fashion. A manometry barostat assembly was positioned in the transverse or...

The negative impact of hydrosalpinx on IVF outcome is well recognized but some reports indicate that tubal infertility with hydrosalpinx is a heterogeneous entity and may have different effects on the outcome. The embryotoxic effects of hydrosalpinx fluid (HF) have been documented in mouse but not human embryos. This study examined the effects of HF on sperm motility and survival after various ...

Background & objectives: Cell phone microwave (MW) is one of the most harmful physical agents in modern society. This study was designed to determine the effects of exposure to cell phone microwaves on mice sperm morphologic indices. Methods: Animals were divided into two groups including: Microwave (MW) (n=6; exposed to 950-MHz cell phone MW with 5 W output power density and 200 KHz modulatio...

this research was carried out to investigate the effects of various levels of dietary organic selenium supplementation (0, 0.1,  0.2 and  0.3 mg/kg) on reproductive traits of rooster. semen was collected using abdominal massage and samples were mixed together. sperm characteristics including percentage of motile, viable and abnormal sperms were assessed. this experiment was carried out based on...

introduction and aims: omeprazole is a gastric parietal cells proton pump inhibitor that is also active against h. pylori in vitro. this study was designed to examine the neutralization of h. pylori cytotoxicity on vero cells by omeprazole micronized in strains isolated from gastritis, ulcer, cancer and barrett's ulcer, to determine whether omeprazole can inhibit vacuolation of the vero cells i...