BACKGROUND Depletion of the circulating actin-binding protein, plasma gelsolin (pGSN) has been described in critically ill surgical patients. We hypothesized that the extent of pGSN reduction might correlate with different outcome of burn patients. The study was performed to evaluate the prognostic implications of pGSN levels on the development of multiple organ dysfunction syndrome (MODS) and ...

OBJECTIVE The aim of this study is to compare the discriminant function of multiple organ dysfunction score (MODS) and sequential organ failure assessment (SOFA) components in predicting the Intensive Care Unit (ICU) mortality and neurologic outcome. MATERIALS AND METHODS A descriptive-analytic study was conducted at a level I trauma center. Data were collected from patients with severe traum...

BACKGROUND Many online interventions designed to promote health behaviors combine multiple behavior change techniques (BCTs), adopt different modes of delivery (MoD) (eg, text messages), and range in how usable they are. Research is therefore needed to examine the impact of these features on the effectiveness of online interventions. OBJECTIVE This study applies Classification and Regression ...

Tests for pleural tuberculosis are insensitive and expensive. We compared nonproprietary microscopic-observation drug-susceptibility (MODS) culture with Löwenstein-Jensen culture for evaluation of pleural specimens. MODS culture was associated with greatly increased diagnostic sensitivity and shorter time to diagnosis, compared with Löwenstein-Jensen culture (sensitivity of culture of biopsy sp...

This paper presents a novel approach, called MODS, to build an accurate time evolving classifier from multiple one-class data streams learning time evolving classifier. Our proposed MODS approach works in two steps. In the first step, we first construct local one-class classifiers on the labeled positive examples from each sub-data stream respectively. We then collect the informative examples (...

Multiple organ dysfunction syndrome (MODS), defined as the presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention, is a cause of high morbidity and mortality in humans and animals. Many advances have been made in understanding the pathophysiology and treatment of this syndrome in human medicine, but much still is unknown. Thi...

A novel algorithm for wide-baseline matching called MODS – Matching On Demand with view Synthesis – is presented. The MODS algorithm is experimentally shown to solve a broader range of wide-baseline problems than the state of the art while being nearly as fast as standard matchers on simple problems. The apparent robustness vs. speed trade-off is finessed by the use of progressively more time-c...

Multiple organ dysfunction syndrome (MODS) is a systemic, dysfunctional inflammatory response that requires long intensive care unit (ICU) stay. It is characterized with high mortality rate depending on the number of organs involved. It has been recognized that organ failure does not occur as an all-or-none rule, but rather a range of organ dysfunction exists resulting in clinical organ failure...

It has long been recognized that major trauma, shock, or burn injury can lead to an acute systemic inflammatory state (SIRS) as well as the multiple organ dysfunction syndrome (MODS). Because of the high mortality rate associated with the development of MODS, for over two decades an intense effort has been devoted towards trying to unravel the underlying mechanisms of this complex syndrome. Alt...

Many of the complications of high-dose therapy with hematopoietic stem cells are caused by or lead to the multiple-organ dysfunction syndrome (MODS). In hematopoietic stem cell transplantation (HSCT), acquired antithrombin III (ATIII) deficiency is independently associated with MODS to the exclusion of transplant type, preparative regimen, and bacteremia. In experimental settings, replacement o...