least squares method (lsm) is an accurate and rapid method for solving some analytical andnumerical problems. this method can be used to estimate the average reservoir pressure in well testanalysis. in fact, it may be employed to estimate parameters such as permeability (k) and porevolume (vp). regarding this point, buildup, drawdown, late transient test data, modified muskatmethod, interferenc...

isoniazid (inh) was studied with regard to its electrochemical treatment on a strongly alkaline solution of a poly (3,4-ethylenedioxythiophene)-modified gold electrode, using both cyclic voltammetry and controlled potential techniques. this composite electrode exhibited 4-fold higher oxidation of inh, in accordance with peak densities, than the bare gold electrode. it was used the central compo...

recently, gasimov and yenilmez proposed an approach for solving two kinds of fuzzy linear programming (flp) problems. through the approach, each flp problem is first defuzzified into an equivalent crisp problem which is non-linear and even non-convex. then, the crisp problem is solved by the use of the modified subgradient method. in this paper we will have another look at the earlier defuzzifi...

Aqueous dispersions of hydrophobic high-molar-mass cellulose-graft-polystyrene (Cel-g-PS) copolymers were prepared by nanoprecipitation from dioxane solutions using sodium dodecyl sulfate as a stabilizer. The size and structure of formed Cel-g-PS nanoparticles were studied by scattering techniques (static and dynamic light scattering, SAXS) and transmission electron microscopy. The scattering a...

A derivation of the nanoprecipitation technique without presence surfactants to reduce nanoparticle size is herein proposed. The absence surfactant in allows capturing particles with a smaller diameter than nanoparticles containing surfactants, facilitating migration antioxidant film packaging. Biodegradable PLA clove oil were produced and characterized by dynamic light scattering, zeta potenti...

Although a number of techniques exist for generating structured organic nanocomposites, it is still challenging to fabricate them in a controllable, yet universal and scalable manner. In this work, a microfluidic platform, exploiting superfast (milliseconds) time intervals between sequential nanoprecipitation processes, has been developed for high-throughput production of structured core/shell ...

Poorly water-soluble drugs such as nitrendipine (~2.0 μg/ml at 37C in water) offer challenging problems in drug formulation as poor solubility is generally associated to poor dissolution characteristics and thus to poor oral bioavailability. To enhance these characteristics, we prepared and evaluated nitrendipine nanosuspension using the nanoprecipitation technique. The important process parame...

The control over the size distribution and stability of polymeric nanoparticles (NPs) is crucial in many of their applications, especially in the biomedical field. These characteristics are typically influenced by the production method and the nature of the starting material. To investigate these aspects, the controlled radical polymerization of functionalized methacrylates constituted by 2-hyd...