In a recent work, Xia and colleagues (1) found that the small GTPase Ran is broadly overexpressed in cancer. In accordance with the emerging evidence that the Ran-GTP signaling pathway may be preferentially exploited in cancer, the authors show that it becomes essential for cell division in transformed, but not in normal, cells. In patients with celiac disease (CD), immune response to gliadin f...

Understanding how natural and anthropogenic drivers affect extant food webs is critical to predicting the impacts of climate change and habitat alterations on ecosystem dynamics. In the Florida Everglades, seasonal reductions in freshwater flow and precipitation lead to annual migrations of aquatic taxa from marsh habitats to deep-water refugia in estuaries. The timing and intensity of freshwat...

The Portsmouth, Rhode Island Mosquito Control Program used granular Bacillus thuringiensis var. israelensis to successfully control salt marsh mosquitoes in a 9 acre salt marsh while monitoring for, planning and implementing small scale open marsh water management in the marsh. Single season larviciding costs were roughly 4% that of contracted open marsh water management in this marsh.

Due to rapidly changing ecosystems, effective environmental protection often calls for the monitoring of vegetation any changes. Vegetation is essential in assessing changes and impacts environmentally valuable ecosystems such as marshlands. While marsh grasses crucial maintenance marshlands, it a tedious time-consuming task that involves careful examination individual pixels within large resol...

UNLABELLED In evaluating conservation and management options for species, practitioners might consider surrogate habitats at multiple scales when estimating available habitat or modeling species' potential distributions based on suitable habitats, especially when native environments are rare. Species' dependence on surrogates likely increases as optimal habitat is degraded and lost due to anthr...

We propose a scenario to form low-mass, single, slow rotating white dwarfs from a solar-like star accompanied by a massive planet, or a brown dwarf, in a relatively close orbit (e.g. HD 89707). Such white dwarfs were recently found by Maxted & Marsh (1998). When the solar-like star ascends the giant branch it captures the planet and the subsequent spiral-in phase expels the envelope of the gian...

BACKGROUND Coeliac disease is defined as a state of immune-mediated hyper-responsiveness to dietary gluten from wheat, barley, or rye in genetically predisposed individuals that results in tissue damage. The diagnosis is made by microscopic examination of a small intestinal biopsy, although serological testing for antibodies against tissue transglutaminase and deamidated gliadin peptide can be ...

This issue of the journal features a spirited debate between Oberhuber and Marsh et al regarding the existence and significance of Oberhuber’s sub-classification of the Marsh III lesion into III a, b, c categories. The controversy stems from an article by Marsh and colleagues in an earlier issue of this journal where they present scanning electron microscopic (SEM) images from two cases classif...