Assuming a conjecture about factorization homology with adjoints, we prove the cobordism hypothesis, after Baez–Dolan, Costello, Hopkins–Lurie, and Lurie.

Costello syndrome (CS) is a rare genetic disorder caused by heterozygous germline Harvey rat sarcoma viral oncogene homolog (HRAS) gene mutations, and characterized by multi-system organ abnormalities. Associated craniofacial, cardiac, neurologic and musculoskeletal abnormalities may pose speci ic anesthetic challenges. Careful pre-anesthetic evaluation and planning is therefore essential to en...

The increasing number of children with Costello syndrome described world wide has helped in delineating further the characteristic features of this condition. We report here two children, seen in the Genetic Division of the Brasilia University Hospital, showing the main features of the syndrome: "coarse" face, redundant skin on the feet and hands, hyperextensible hand and finger joints, curly h...

Costello EJ, Mustillo S, Erkanli A, et al. Prevalence and development of psychiatric disorders in childhood and adolescence. Arch Gen Psychiatry 2003;60:837–44. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Costello syndrome is a congenital disorder comprising a characteristic face, severe feeding difficulties, skeletal, cardiac and skin abnormalities, intellectual disability and predisposition to malignancies. It is caused by heterozygous germline HRAS mutations mostly affecting Gly(12) or Gly(13), which impair HRAS-GTPase activity and result in increased downstream signal flow independent of inc...

in this study, undoped zno and doped with fe and mn nanostructures were synthesized by hydrothermal method. the morphology of nanostructures was characterized by scanning electron microscope. the electrochemical response of the carbon paste electrode modified with nanoparticles of zno and also zno doped with fe and mn toward levodopa (l-dopa) was studied. studies of cyclic voltammetry using pro...

Le syndrome de Costello appelé également syndrome Facio-cutanéo-squelettique est une anomalie rare du développement d’origine génétique de transmission autosomique dominante. Sa prévalence est inconnue mais environ 250 cas ont été rapportés dans la littérature. La majorité des cas sont sporadiques. Les principaux signes sont une dysmorphie faciale caractéristique, un retard mental, un retard de...

This bulletin is based on research conducted by Associate Professor Steven Rowley and Associate Professor Greg Costello at the AHURI Research Centre—Curtin University, Associate Professor David Higgins at the AHURI Research Centre—RMIT University, and Professor Peter Phibbs at the AHURI Research Centre—The University of Sydney. This research explored how property finance decisions are made and ...