ATP-binding cassette (ABC) transporters are molecular pumps that harness the chemical energy of ATP hydrolysis to translocate solutes across the membrane. The substrates transported by different ABC transporters are diverse, ranging from small ions to large proteins. Although crystal structures of several ABC transporters are available, a structural basis for substrate recognition is still lack...

Cross-terms lie between two auto-components and are oscillatory, with their frequencies increasing with increasing distance in time-frequency between the two components. The cross-terms can have a peak value as high as twice that of the auto-components. A Wigner distribution of a two-component signal is shown in Figure 1. In this figure, it is easy to separate the auto-components from the cross...

Background: There has been a resurgence of interest in the use mechanical bowel preparation (MBP) and antibiotics before elective colorectal surgery. In era antibiotics, MBP is controversial. Aims Objectives: The aim current study was to analyze effect over “no MBP” on outcome patients undergoing Materials Methods: This an institution-based prospective, randomized comparative study. Fifty patie...

background one disadvantage of expressing heterologous proteins in escherichia coli is that the proteins are frequently expressed as insoluble inclusion bodies. to avoid this problem, heterologous proteins are typically expressed as a fusion protein. maltose binding protein (mbp) is one of the widely used partners for production of recombinant fusion proteins in e. coli. mbp is among the most e...

this paper, i have focused on the tax side of the fiscal policy to  investigate the past and future behavior of fiscal sustainability in iran. to do so, i have employed two different forward-looking and backward-looking approaches. first, the backward-looking approach is the fiscal policy rule proposed by daving & leeper (2011). precisely, this rule determines that whether the fiscal policy is ...

Several works published over the last two decades have shown for a stylized set-up with homogeneous users that metering-based priority (MBP) schemes may generate Pareto improving departure time adjustments similar to those induced by congestion pricing, but without any financial transaction. We investigate whether MBP (i) still generates significant savings and (ii) remains Pareto-improving, va...

This paper considers the backward error analysis of stochastic differential equations (SDEs), a technique that has been of great success in interpreting numerical methods for ODEs. It is possible to fit an ODE (the so called modified equation) to a numerical method to very high order accuracy. Backward error analysis has been particularly valuable for Hamiltonian systems, where symplectic numer...

Objective: Multiple sclerosis (MS) is presented with motor and sensory function loss. It is caused by demyelination and following axonal lesion. As myelin basic protein (MBP) is one of the key elements of the myelin cover, we examined the level of MBP in serum, stimulated, and unstimulated saliva as a suitable biomarker for detecting MS. Methods: A case-control study was performed in 29 health...