OBJECTIVE To evaluate the course and identify determinants of community integration for up to 3 years following moderate to severe traumatic brain injury. DESIGN Prospective cohort study. PATIENTS A total of 119 moderate to severe traumatic brain injury patients aged 16-67 years. METHODS The Community Integration Questionnaire was completed at 3, 6, 12, 18, 24 and 36 months post-injury. R...

OBJECTIVE To evaluate spine magnetic resonance imaging (MRI) inter-reader and intra-reader reliabilities using the thoracolumbar injury classification system and severity score (TLICS) and to analyze the effects of reader experience on reliability and the possible reasons for discordant interpretations. MATERIALS AND METHODS Six radiologists (two senior, two junior radiologists, and two resid...

The aim of the study was to evaluate the quality of life of children after mild and moderate traumatic brain injury (TBI) and an analysis of the specific assessment of individual areas of functioning in these children’s perception. This subject is important both in terms of the further education of the children but also in terms of their adapting to life after brain injury. We tested 20 childre...

conclusions m30 levels were higher in cvhb patients compared to healthy controls. however, m30 levels were similar in the mild and moderate stages of fibrosis, so they did not indicate the severity of underlying fibrotic or inflammatory processes in cvhb patients. results the mean ages of patients and controls were 39.7 and 45.7 years, respectively, and 35% of the controls and 52% of the patien...

in the natural disasters such as earthquake, based on severity of trauma, time under the rubble and quality/quantity of hydratation we will confront with a spectrum of traumatic rhabdomyolysis. in present study we evaluate victims of bam earthquake to show different stage of muscle trauma, from minor trauma with almost normal level of muscle enzyme to those with moderate trauma leading to crush...

objectives we aim to evaluate the role of glibenclamide on the short-term outcome of patients with dai due to moderate to severe tbi. patients and methods in this controlled randomized clinical trial, 40 patients with moderate to severe tbi were assigned to glibenclamide (n = 20) and control (n = 20) groups. six hours after admission the intervention group received 1.25 mg glibenclamide every 1...

Background & Aim: Traumatic brain injury is one of the main causes of death and disability. The aim of this study is to systematically review the articles which assessed some serum factors of traumatic brain injury patients in relation to their outcomes. Methods & Materials/Patients: Databases were searched for relevant publications from 2005 to 2014. Selection criteria were:Studies which ev...

Dysfunction in the motor system is a feature of persistent whiplash associated disorders. Little is known about motor dysfunction in the early stages following injury and of its progress in those persons who recover and those who develop persistent symptoms. This study measured prospectively, motor system function (cervical range of movement (ROM), joint position error (JPE) and activity of the...

Astrocytes respond to traumatic brain injury (TBI) by altered gene expression, hypertrophy and proliferation that occur in a gradated fashion in relation to the severity of the injury. Both beneficial and detrimental effects have been attributed to reactive astrocytes, but their roles after brain injury are not well understood. To investigate these roles, we determined the effects on cortical t...