objective(s): the wide scale use of zinc oxide nanoparticles (zno nps) in the consumer market world makes human beings more prone to the exposure to zno nanoparticles and its adverse effects. therefore, the aim of the present study is to assess renal toxicity potential of zno and polyethylene glycol coated zno nanoparticles in rat.materials and methods: co-precipitation chemical method was used...

The apple is the most widely used fruit globally. Apples are more prone to fungal spoilage, which leads browning and subsequent changes in their flavor texture. Browning also caused by tyrosinase enzyme. By inhibiting initiation spoilage fruits, natural texture of fruits can be maintained. Biogenic NPs act as antioxidants inhibit due oxidative stress, it catalyzes deformation hyphae spores. Nan...

Nanoparticles (NPs) have received more attention as antiparasitic agents. In the present study, silver and copper nanoparticles were synthesized and characterized using scanning electron microscopy (SEM), transmission electron microscope (TEM) and X-ray fluorescence (XRF). The antiparasitic activity of Ag and CuO nanoparticles were tested against two of the most environmentally spread parasites...

Novel magnetic composite nanoparticles (MCPs) were successfully synthesized by ex situ conjugation of synthesized ZnO nanoparticles (ZnO NPs) and Fe3O4 NPs using trisodium citrate as linker with an aim to retain key properties of both NPs viz. inherent selectivity towards cancerous cell and superparamagnetic nature, respectively, on a single system. Successful characterization of synthesized na...

Background and Aims: Although metal and metal oxide nanoparticles are used in different medical applications, they may have considerable toxicity on various cells, such as myocytes. Therefore, this study aimed to evaluate the toxicity of the naked and serum-treated silver nanoparticles (Ag NPs) and magnesium oxide nanoparticles (MgO NPs) on the cardiomyocytes. Materials and Methods: Cardiomy...

BACKGROUND The aim of this study is to evaluate the anticancer activity of vorinostat-incorporated nanoparticles (vorinostat-NPs) against HuCC-T1 human cholangiocarcinoma cells. Vorinostat-NPs were fabricated by a nanoprecipitation method using poly(DL-lactide-co-glycolide)/poly(ethylene glycol) copolymer. RESULTS Vorinostat-NPs exhibited spherical shapes with sizes <100 nm. Vorinostat-NPs ha...

Due to overexpression of glycyrrhetinic acid (GA) receptor in liver cancer cells, glycyrrhetinic acid modified recombinant human serum albumin (rHSA) nanoparticles for targeting liver tumor cells may result in increased therapeutic efficacy and decreased adverse effects of cancer therapy. In this study, doxorubicin (DOX) loaded and glycyrrhetinic acid modified recombinant human serum albumin na...

the use of biogenic selenium nanoparticles for various purposes is going to be an issue of considerable importance; thus, appropriate simple methods should be developed and tested for the synthesis and recovery of these nanoparticles. in this study, a fungus was isolated from a soil sample, identified as aspergillus terreus and used for extracellular synthesis of selenium nanoparticles (se nps)...

Superparamagnetic Fe3O4 nanoparticles (NPs) based nanomaterials have been exploited in various biotechnology fields including biomolecule separation. However, slow accumulation of Fe3O4 NPs by magnets may limit broad applications of Fe3O4 NP-based nanomaterials. In this study, we report fabrication of Fe3O4 NPs double-layered silica nanoparticles (DL MNPs) with a silica core and highly packed F...

The development of dual-imaging enabled cancer-targeting nanoparticles (DICT-NPs) is reported based on newly developed biodegradable photoluminescent polymers and superparamagnetic iron oxide nanoparticles. DICT-NPs possess capabilities of dual-imaging (magnetic resonance imaging and optical imaging), magnetic targeting, and potentially selective targeting for cancer cells. The development of D...