Repair of ultraviolet light-induced damage to DNA was studied in three melanoma lines, a mammary carcinoma line, EMT6, and a normal lung fibroblast line, MLF, all from the mouse. The melanomas were B16CL4, a gamma-ray-resistant clonal line derived from B16; S91H-, an auxotrophic line derived from Cloudman S91; and HP, a freshly isolated line from s.c. grown Harding-Passey melanoma. The melanoma...

A 60-year-old man complaining of diplopia and vertigo showed bilateral medial longitudinal fasciculus (MLF) syndrome. The CT scan revealed a space-occupying lesion with watery fluid in the left cranial fossa, which was divided into two parts by a thin septum. Surgical trepanation was performed followed by 4 weeks of prednisolone therapy. He was completely cured 5 months later. The plausible cau...

The present case describes a patient with one and a half syndrome due to pontine granuloma (neurocysticercosis). In one and a half syndrome, the lesion affects the paramedian pontine reticular formation (PPRF) (or the abducens nucleus) and the medial longitudinal fasciculus (MLF) on the same side (the MLF having crossed from the opposite side). It is most often caused by multiple sclerosis, bra...

In this paper, a reactive control architecture based on hybrid systems (continuous/discrete) is used to control a unicycle mobile robot tracking a given trajectory while avoiding obstacles. The main motivation of using hybrid systems is the possibility to define the overall control scheme as a combination of several elementary controllers (trajectory tracking, obstacle avoidance) that stability...

Ecology of the lactic acid bacteria (LAB) during alcoholic fermentation (AF) and spontaneous malolactic fermentation (MLF) of Tempranillo wines from four wineries of La Rioja has been studied analyzing the influence of the winemaking method, processing conditions, and geographical origin. Five different LAB species were isolated during AF, while, during MLF, only Oenococcus oeni was detected. A...

BACKGROUND The medial vestibulospinal tract (MVST), which descends in the medial longitudinal fasciculus (MLF), may mediate the vestibular evoked myogenic potentials (VEMPs) in the contracting sternocleidomastoid muscle. We report herein abnormal VEMPs in a patient with medial medullary infarction (MMI) that appeared to involve the MLF. CASE REPORT A patient with infarction involving the righ...

The association of internuclear ophthalmoplegia (INO) with torsional nystagmus is rare. We report the case of a 63-year-old man presenting with sudden onset of diplopia. On ocular examination, he had left INO and a torsional nystagmus with counter-clockwise quick-phases from the patient's point of view in the primary position, ipsiversive to the side of the medical longitudinal fasciculus (MLF)...

This paper describes a parallel cross-validation (PCV) procedure, for testing the predictive ability of multi-layer feed-forward (MLF) neural networks models, trained by the generalized delta learning rule. The PCV program has been parallelized to operate in a local area computer network. Development and execution of the parallel application was aided by the HYDRA programming environment, which...

The complex array of neuronal connections in the vertebrate brain derives from a simple, conserved scaffold of axon tracts in the early embryonic brain. The mechanisms governing the formation of these tracts are largely unknown. We are interested in the molecular cues responsible for the formation of the early axon tracts, in particular in linking transcription factors that are expressed in a s...

OBJECTIVE To test the validity of diffusion tensor imaging (DTI) measures of tissue injury by examining such measures in a white matter structure with well-defined function, the medial longitudinal fasciculus (MLF). Injury to the MLF underlies internuclear ophthalmoparesis (INO). METHODS 40 MS patients with chronic INO and 15 healthy controls were examined under an IRB-approved protocol. Tiss...