Cancer is one of the major causes mortality and morbidity in world. Pain most debilitating exhausting symptom cancer. It also has deep intense impact on patient’s quality life. In advanced stages cancer, incidence pain approaches up to 70–80%. can be effectively treated by expert hands. Strong opioids are mainstay WHO analgesic ladder, specifically for cancer patients. Unfortunately, developing...

Misery is not miserly: Sadness increases the amount of money that decision makers give up to acquire a commodity. The present research investigated when and why the misery-is-not-miserly effect occurs. Drawing on William James's concept of the material self, we tested a model specifying relationships among sadness, self-focus, and the amount of money that decision makers spend. Consistent with ...

OBJECTIVES In major cerebral arterial occlusive diseases, patients with inadequate blood supply relative to metabolic demand (misery perfusion) may be at increased risk for cerebral ischaemia. This study investigated whether patients showing misery perfusion on PET have a high risk of recurrent ischaemic stroke. METHODS The relation between the regional haemodynamic status of cerebral circula...

Adverse psychosocial exposure or "misery" is associated with physical disease. This association may not be causal. Rather it may reflect issues of reverse causation, reporting bias, and confounding by aspects of the material environment typically associated with misery. A non-causal relation will not form the basis of effective public health interventions. This may be why psychosocial intervent...

İktisat kuramına 1970’li yıllarda Arthur Okun tarafından kazandırılan Hoşnutsuzluk Endeksi (Economic Discomfort Index = EDI) ile kronolojik olarak ardından literatüre giren Sefalet (Misery Index), makro ekonomik sağlıksızlığı temsil edebilen ve orijinal haliyle temelde enflasyon oranı işsizlik değişkenlerinin toplanmasına dayalı oluşturulmuş endekslerdir. bileşenlerinin münferit ele alınarak ta...

Prominent structural models of depression and anxiety arise from 2 traditions: (a) the tripartite/integrative hierarchical model based on symptom dimensions, and (b) the fear/anxious-misery model based on diagnostic comorbidity data. The tri-level model of depression and anxiety was developed to synthesize these structural models, postulating that narrow (disorder-specific), intermediate (fear ...