background & aim:vaginal disease has always been a great concern of women. medicinal plants as natural resources with fewer side effects can effectively treat these infections given the diversity of these infections, resistance to antibiotics and side effects of existing drugs. the present study aimed to compare antimicrobial effects of methanol extract of francoeuria undulata on growth of seve...

Whey, is a natural product resulting from coagulation of milk. Herein, whey powder prepared by non thermal method, was optimized and investigated for its anti-microbial potential against twelve bacerial isolates belonging to three bacterial species by agar-well diffusion assay. Minimum Inhibitory Concentration values were determined by tissue culture plate method to check the concentration rang...

conclusions our experimental and in silico findings may provide new insight in the complex molecular pathways of drug resistance and also could assist design an efficient therapeutic strategy for aspergillosis treatment. results four out of five isolates revealed cyp51a and mdr1 mrna overexpression. interestingly, the isolate, which was negative for cyp51a and mdr1 mrna expression showed a high...

background and purpose: candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. nowadays, because of increased fungal resistance to antibiotics, the use of herbal medicine has gained particular attention. cyclamen species are medicinal plants containing triterpenoid saponins, which are shown to have antimicrobial properties. materials ...

background many efforts have been made by researchers to find new antibiotics which are clinically useful against bacteria and drug resistant microorganisms. objectives we aimed to evaluate the antimicrobial effects of hydroalcoholic extracts of leaves and seeds of the portulaca oleracea plant in traditional medicine of sistan region, southeast of iran. materials and methods in this cross-secti...

In recent years, the spread of drug-resistant strains of Streptococcus pneumoniae, as the most common causes of bacterial respiratory infections, threatens public health. Therefore, the use of new antimicrobial medicines to inhibit this pathogen is an urgent demand. In this research project, the inhibitory effects of thirty recently synthesized compounds including thiazole, thiazolidine, imidaz...

Purpose To limit corneal damage and potential loss of vision, bacterial keratitis must be treated aggressively. Innovation in antimicrobials is required due to the need for empirical treatment and the rapid emergence of bacterial resistance. Designed host defense peptides (dHDPs) are synthetic analogues of naturally occurring HDPs, which provide defense against invading pathogens. This study in...

introduction: in this study, the chemical composition and antimicrobial activity of essential oil of ziziphora clinopodiodes and its potential application as a natural preservative in reducing the indigenous microbial population of hamburger were investigated. method: essential oil of ziziphora clinopodiodes cultivated in iran was obtained by hydro-distillation method (hdm). chemical compositio...

abstract       background and objective: due to the continuous increase of multidrug-resistant acinetobacter baumannii strains around the world, decision making for an effective treatment of infections caused by this organism depends on the results of antimicrobial susceptibility tests. in this study, the validity of disk diffusion and e-test methods was assessed by their comparison with the re...

The emergence of multidrug-resistant Gram-negative bacteria, in particular Acinetobacter baumannii and Pseudomonas aeruginosa, is a critical clinical problem worldwide. Antimicrobial peptides (AMPs) have received increasing attention due to their ability to overcome multidrug-resistant microbes. We recently reported that cysteine-functionalized alpha-helical peptides LLKKLLKKC and CLLKKLLKKC ef...