New chlorine-containing furanones were tested for the presence of antibacterial activity and also for genotoxicity in Ames test. It has been established that the tested compounds had antibacterial properties. Antibacterial activities of all four compounds differed in rich broth and minimal glucose media. While in rich broth the minimal inhibitory concentration (MIC) of the compounds varied from...

objective: infections are increasing caused by antibiotic-resistant pseudomonas aeruginosa day by day. for this reason, many researchers have tried to find new compounds as alternative antibiotics. the purpose of this study was to evaluate the effect of yarrow extract, green tea and ajowan  on pseudomonas aeruginosa. methods: extraction  of achillea, green tea and ajowan was done with rotary. f...

minimum inhibitory concentrations (mic) of some essential oils and citric acid were determined against two micro-organisms associated with spoilage of orange juice (saccharomyces cervisiae and leuconostoc mesenteroids) and against four unidentified microorganisms isolated from citrus surface and spoiled orange juice. mic for limonene were obtained less than 5% w/v aqueous against saccharomyces ...

BACKGROUND Medicinal plants are used worldwide for several human ailments including bacterial infections. The present work was designed to assess the in vitro antibacterial activities of some Cameroonian medicinal plants including Entada abyssinica, Entada africana, Pentaclethra macrophylla, Allexis cauliflora, Anthocleista leibrechtsiana, Carapa procera, Carica papaya and Persea americana agai...

Bacterial antibiotic resistance is typically quantified by the minimum inhibitory concentration (MIC), which is defined as the minimal concentration of antibiotic that inhibits bacterial growth starting from a standard cell density. However, when antibiotic resistance is mediated by degradation, the collective inactivation of antibiotic by the bacterial population can cause the measured MIC to ...

The physicochemical properties, composition and antimicrobial activity of cinnamon essential oil (Cinnamomum zeylanicum) were studied. The bioactivity of this essential oil against Paenibacillus larvae was analyzed by means of a combination of in vitro techniques, such as the tube dilution method and bioautography, a method employed to localize antibacterial activity on a chromatogram. Cinnamal...

In different fungal and algal species, the intracellular concentration of reduced glutathione (GSH) correlates closely with their susceptibility to killing by the small molecule alkylating agent 3-bromopyruvate (3BP). Additionally, in the case of Cryptococcus neoformans cells 3BP exhibits a synergistic effect with buthionine sulfoximine (BSO), a known GSH depletion agent. This effect was observ...

Microcin J25 (MccJ25) is a small ribosomally synthesized antimicrobial peptide that is produced by Enterobacteriacea family especially E.coli. The present study focuses on preparation and evaluation of in vitro antimicrobial and biological properties of a new peptide derived from MccJ25. We prepared a MccJ25-derived peptide containing 14 amino acids and a single intra-molecular disulfide bond a...