BACKGROUND This study, by regulating the expression level of microRNA-21 (miRNA-21) in antigen-1+ (Sca-1+) cardiac stem cells (CSCs), examined the role of miRNA-21 in migration, proliferation, and differentiation of Sca-1+ CSCs, and explored the use of miRNA-21 in treatment of heart-related diseases in mice. MATERIAL AND METHODS The CSCs of 20 healthy 2-month-old C57BL/6 mice were collected in ...

Communications via Microsoft PowerPoint (PPT for short) documents are commonplace, so it is crucial to take advantage of PPT documents for information security and digital forensics. In this paper, we propose a new method of text steganography, called MIMIC-PPT, which combines text mimicking technique with characteristics of PPT documents. Firstly, a dictionary and some sentence templates are a...

This study employs the use of two methods of canonical correlation analysis to investigate the relationship between two latent variables: corporation “size” and “profitability”. The variables examined are divided into an independent set of variables representing the latent variable “size”, and a dependent set of variables representing the latent variable called “profitability”. The first method...

The promoter region of the imprinted gene MEST contains several motifs capable of forming G-quadruplex (G4) structures, which appear to contribute to consistent allelic dropout during polymerase chain reaction (PCR) analysis of this region. Here, we extend our previous analysis of MEST G4 structures by applying fluorescent footprinting techniques to assess non B-DNA structure and topology in ds...

Abstract Background lncRNAs have important roles in regulating cancer biology. Accumulating evidence has established a link between the dysregulation of and microRNA progression. In previous studies, miR-7-5p been found to be significantly down-regulated mesenchymal-like lung cell lines directly regulated EGFR . this work, we investigated lncRNA partner progression cancer. Methods We expression...

Background: Lassa virus disease (LVD) is of public health concern in endemic countries Africa. Majority infections are asymptomatic while symptomatic cases can mimic other infections. This study was aimed at determining the clinical features seen children with positive PCR and symptoms that determine outcome LVD an community, Southeast Nigeria.
 Materials methods: It a prospective observat...

abstract  background and objectives malignant lymphoma may be very difficult to be diagnosed through routine histopathological methods because they may mimic reactive architecture or contain reactive infiltrates. detection of the monoclonal lymphocyte population is one of the best methods of diagnosis since a monoclonal proliferation is strongly suggestive of neoplasia. by means of a pcr method...

In the current study, we aimed at elucidating the regulatory mechanisms through which microR-1187 (miR-1187) participates in hepatocyte apoptosis in acute liver failure (ALF). An ALF model was induced with D-galactosamine (D-GalN) plus lipopolysaccharide (LPS) in BALB/c mice. The hepatic miRNA expression profile was detected by microarray analysis and verified by quantitative real-time PCR (qRT...