Nitrogenated heterocyclic compounds are present in both natural and synthetic drugs, and hexahydropyrimidine derivatives may prove to be efficient in treating dermatomycosis causing fungi. This study evaluated the antifungal activity of four hexahydropyrimidine derivatives against the dermatomycosis causing fungi. These derivatives were synthesized, characterized, and assessed in terms of their...

A survey of Microsporum gypseum was conducted in soil samples in different geographical regions of Brazil. The isolation of dermatophyte from soil samples was performed by hair baiting technique and the species were identified by morphology studies. We analyzed 692 soil samples and the recuperating rate was 19.2%. The activities of keratinase and elastase were quantitatively performed in 138 sa...

A 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. During that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermatitis at other hospitals, and had been treated with agents that included acitretin and prednisone. Finally, fungi were found in the lesions by optical microscopy, and the fungal cult...

Report of a case of tinea corporis caused by Microsporum gypseum in a 36-year-old female Aids patient. The literature does not refer this dermatophyte as a common etiologic agent in this group of patients.The lesions were generalized,psoriasiform and refractory to treatment with ketoconazole and itraconazole.

Prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in Jaen was investigated during a period of three years (1996-1999). The prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. The isolated species were: Microsporum canis (48.6%), Trichophyton mentagrophytes (27.1%), Epidermophyton floccosum (10%), Trichophyton rubrum (8.6%), Tricho...

Tinea capitis (TC) is the dermatophytosis widespread in the world[1,2]. Not only specter of causative species in a specific geographical area is changing in time, but also the distribution of each one worldwide. No data exists on TC for recent 25 years in our country. Following goals were set for the study: to determine the specter of TC causatives and importance of age and sex in disease devel...

conclusions our findings showed that streptomyces has antifungal effects against m. canis. results in this study the most antagonist of actinomycete isolates with antifungal activity against m. canis isolates of l1, d5, ks1m, km2, kn1, ks8 and ks1 were shown in vitro. electron microscopic studies showed that some fungal strains form spores, mycelia and spore chain. nucleotide analysis showed th...

Peganum harmala (Zygophyllaceae) is an intriguing herb with a long history of medicinal use. Antifungal activity of P. harmala seed extract against certain fungal species was investigated in vitro. Antifungal activity of the extract of P. harmala seeds was investigated against several fungal species using in vitro agar dilution technique. The fungal species included: Microsporum canis, Microspo...

Peganum harmala (Zygophyllaceae) is an intriguing herb with a long history of medicinal use. Antifungal activity of P. harmala seed extract against certain fungal species was investigated in vitro. Antifungal activity of the extract of P. harmala seeds was investigated against several fungal species using in vitro agar dilution technique. The fungal species included: Microsporum canis, Microspo...