Micronutrients, including minerals and vitamins, are indispensable to DNA metabolic pathways and thus are as important for life as macronutrients. Without the proper nutrients, genomic instability compromises homeostasis, leading to chronic diseases and certain types of cancer. Cell-culture media try to mimic the in vivo environment, providing in vitro models used to infer cells' responses to d...

OBJECTIVES To investigate whether the micronutrients that were shown to reduce the risk of development of age-related macular degeneration in the Age-Related Eye Disease Study (AREDS) can have the same effect on the development of diabetic retinopathy in rats, and to understand the possible mechanisms. METHODS Streptozotocin-induced diabetic rats received a powdered diet with or without suppl...

BACKGROUND There are reports showing that l-carnitine alone or in combination with other micronutrients improve sperm parameters. However, comparative studies are still lacking. This study was carried out to compare the short term effects of a combination of eight micronutrients including l-carnitine vs. a mono-substance (l-carnitine alone) on sperm parameters. METHODS This was a prospective,...

in order to study the effects of different levels of cow and chicken manure and elemental sulfur (s) on availability of plant nutrients and their uptake by corn (zea mays l.), a factorial experiment was conducted using a completely randomized design and three replication. experimental treatments were three levels (0, 10 and 20 ton ha-1) of cow and chicken manures, and three levels (0, 0.25% and...

It is known that deficiencies of micronutrients due to infections increase morbidity and mortality. This phenomenon depicts itself conspicuously in developing countries. Deficiencies of iron, vitamins A, E, C, B12, etc are widely prevalent among populations living in the third world countries. Helicobacter pylori (H pylori) infection has a high prevalence throughout the world. Deficiencies of s...

Diets very rich in cereals have been associated with micronutrient malnutrition, and the biofortification of them, has been proposed as one of the best approaches to alleviate the problem. Durum wheat is one of the main sources of calories and protein in many developing countries. In this study, 46 durum varieties grown under full and reduced irrigation, were analyzed for micronutrients and phy...

The oral cancer is one of the most prevalent type of cancer worldwide. It is invariably linked to lifestyle habits like alcohol consumption, cigarette smoking and poor nutritional status. This apart, the role of micronutrients in oral carcinogenesis still remains less understood. So the study was undertaken to assess the micronutrient levels of oral cancer and precancerous patients.The estimati...

Diet can affect a spectrum of biological processes ranging from behavior to cellular metabolism. Yet, the precise role of an individual dietary constituent can be a difficult variable to isolate experimentally. A chemically defined food (CDF) permits the systematic evaluation of individual macro- and micronutrients. In addition, CDF facilitates the direct comparison of data obtained independent...