This report is a detailed review of the current data on the mechanic and gravitational sensitivity of osteoblasts and osteogenic precursor cells in vitro. It summarizes the numerous responses of cells with an osteoblastic phenotype and osteogenic precursor cells and especially their responses to the alteration of their mechanic or gravitational surroundings. The review also discusses the osteog...

Development of efficient means for the recovery of valuable resources from solid waste materials is a critical requirement for future Advanced Life Support (ALS) systems that will be needed to support long-duration manned mission in space. Of particular importance are technologies that may be employed in hypogravity and microgravity environments. Currently three solid waste processing technolog...

Research in microgravity is indispensable to disclose the impact of gravity on biological processes and organisms. However, research in the near-Earth orbit is severely constrained by the limited number of flight opportunities. Ground-based simulators of microgravity are valuable tools for preparing spaceflight experiments, but they also facilitate stand-alone studies and thus provide additiona...

Fluid transport and handling in extraterrestrial conditions, i.e. microgravity, require significantly different system engineering than here on Earth. On Earth, a notable part of fluid processing units inherently relies buoyancy to handle fluids. In space, however, effects are negligible due the strong diminishment gravity, resulting domination surface tension forces. Surface forces also domina...

Ve propose an experimental system of a space robot in the microgravity environment at the Japan Microgravity Center (JAMIC), where the microgravity k e p t as accurate as ~ o ~ G for 10 secondsis generated by 49Om-depth free-fall. We developed a system for experiments of free-flyers at the JAMIC. In this paper, we take up two important topics to perform the experiments. The first one is to rele...

Network structures created by hydroxycinnamate cross-links within the cell wall architecture of gramineous plants make the cell wall resistant to the gravitational force of the earth. In this study, the effects of microgravity on the formation of cell wall-bound hydroxycinnamates were examined using etiolated rice shoots simultaneously grown under artificial 1 g and microgravity conditions in t...

BACKGROUND AND AIMS Gravity contributes to the maintenance of bone integrity. Accordingly, weightlessness conditions during space flight accelerate bone loss and experimental models in real and simulated microgravity show decreased osteoblastic and increased osteoclastic activities. It is well known that the endothelium and bone cells cross-talk and this intercellular communication is vital to ...

Microgravity offers excellent advantages for tissue engineering by modulating cellular morphology, metabolism, secretion, proliferation, and stem cell differentiation. In article 2202768 Yannan Zhao, Jianwu Dai co-workers, current simulated-microgravity devices cutting-edge advances of microgravity biomaterials-dependent or biomaterials-independent are summarized discussed to offer a reference ...

AstEx is a microgravity experiment selected to fly on ESA’s 51st Microgravity Research Campaign in November 2009. The experiment will investigate the dynamics of regolith on asteroid surfaces. Despite their very low surface gravities, asteroids exhibit a number of different geological processes involving granular matter. Understanding the mechanical response of this granular material subject to...