introduction: diabetic retinopathy (dr) is the single largest cause of sight loss and blindness in the working age population of western countries; it is the most common cause of blindness in adults between 20 and 60 years of age. early diagnosis of dr is critical for preventing vision loss so early detection of microaneurysms (mas) as the first signs of dr is important. this paper addresses th...

BACKGROUND AND PURPOSE Intracranial aneurysms have been induced in mice, rats, rabbits, and primates through carotid artery ligation. We reviewed our experience with RCCA ligation to quantify the rate of aneurysm formation in rabbits. MATERIALS AND METHODS In 30 consecutive New Zealand white rabbits, the RCCA was ligated during surgery to create elastase-induced aneurysms. The basilar artery ...

Timely detection and treatment of microaneurysms (MA) is a critical step to prevent the development of vision-threatening eye diseases such as diabetic retinopathy. However, detecting MAs in fundus images is a highly challenging task due to the large variation of imaging conditions. In this paper, we focus on developing an interleaved deep mining technique to cope intelligently with the unbalan...

Ocular ischemic syndrome (OIS) is characterized by ocular symptoms and signs that are secondary to severe carotid artery obstruction. We report a 69-year-old man who suffered from progressively blurred vision in both eyes. Fundus examination showed scattered areas of retinal hemorrhage, some with a white center, in both eyes. Fluorescence angiography revealed multiple microaneurysm-like hyperfl...