background: the opening and closing of the implantation window is important for successful pregnancy in eutherians. the recent study demonstrated that the window of uterine receptivity was prepared by the sole action of progesterone in mice, but the mechanism to close the window remained to be elucidated. methods: the pregnant mice were ovariectomized on the evening on the third day of pregnanc...

background: the ovariectomized animals are good models to evaluate the effect of different steroid hormone treatments on implantation events and the pattern of integrin expression. therefore, this study was performed to compare the expression of integrins and osteopontin (opn) in correlation with pinopode development in ovariectomized mice endometrium which was subjected to steroid hormones. me...

Metastatic carcinoma from extragenital sites to the uterus, particularly endometrium, is rare and usually a sign of advanced disease. It necessary differentiate between metastatic primary tumours since treatment prognosis are entirely different. We discuss case 61-year-old woman who presented with postmenopausal bleeding due breast cancer endometrium. She had been diagnosed on tamoxifen for six...

background thymus species are well known medicinal plants which the previous studies suggested the involvement of the opioid system in them. objectives this study aimed to investigate the effects of methanolic extract and essential oil of aerial parts of thymus daenensis (td), an endemic aromatic medicinal plant of iran, on morphine withdrawal syndrome in mice. materials and methods experiments...

We presents results of a study on endometritis modeling in rats with double intravaginal administration bacterial lipopolysaccharide (LPS). The established endometrial inflammatory process was accompanied by decrease the weight animals, an increase uterus, neutrophilic infiltration, edema, and overexpression cyclooxygenase endometrium 30-45 days after start induction. Local use plasma enriched ...

previous studies have shown that the extract of papaver rhoeas reduces morphine dependence, locomotor activity and reward. in present study, the effects of hydro-alcohol extract of papaver rhoeas on the tolerance to analgesic effects of morphine in mice have been investigated using tail flick method. subcutaneous (s.c.) administration of morphine (1, 2, 5 and 10 mg/kg) induced analgesia. howeve...

Introduction and Aim: Dendritic cells (DCs) are heterogenous group of accessory that function as specialized forms antigen-presenting in human body. A thorough knowledge the DC population uterus, especially CD83 would be very useful for an effective understanding immune protection endometrium during different phases menstrual cycle pathological conditions uterus. Materials Methods: prospective ...

background: aggressive embryo and receptive endometrium are necessary for successful implantation. on this time endometrium transformates to receptive state, which permits embryonic implantation. studies about embryonic implantation and endometrial receptivity are always a hot spot in the field of reproductive medicine. objective: to investigate the expression pattern of meis1 during peri-impla...

Early pregnancy is characterized by an increase in the blood volume of the uterus for embryonic development, thereby exerting fluid shear stress (FSS) on the vascular walls. The uterus experiences vascular remodeling to accommodate the increased blood flow. The blood flow‑induced FSS elevates the expression of vascular endothelial growth factors (VEGFs) and their receptors, and regulates vascul...