An experiment was carried out to evaluate the serum total protein, glucose, liver, kidney and haematological response varied levels of exogenous L-Selenomethionine (L-SeMet). Twenty four male rabbit bucks, about 10 months old were randomly allotted treatments in a completely randomized design. Blood samples collected at day 21 42 from bucks processed for haematocrit, haemoglobin, erythrocytes, ...

Purpose: Cognitive deficit is one of the common comorbidity accompanying epilepsy. The present study evaluated the effect of Celastrus paniculatus (C- paniculatus) seed extract on seizure severity and cognitive deficit following Pentylenetetrazole (PTZ) -induced chemical kindling model. Methods: PTZ kindling model was developed by daily administration of sub-convulsive dose of PTZ 30 mg/kg for...

OBJECTIVE Determine the effect of a matrix metalloproteinase inhibitor (MMPi) and angiotensin converting enzyme inhibitor (ACEi) on collagen, MMP, tissue inhibitors of MMPs (TIMPs) expression in the spontaneously hypertensive heart failure (SHHF) rat. METHODS Six groups were tested: normotensive 9- and 13-month-old Wistar-Furth (WF) rats, 9-month-old SHHFs (compensatory hypertrophy), 13-month...

Comparative Effects of Diaxepam and Midazolam on Paraoxon Toxicity in Rats. KRUTAKKROL, H., AND DOMINO, E. F. (1985). Toxicol. Appl. Pharmacol. 81,545-550. The present study was undertaken to compare the effectiveness of a new water-soluble benzodiazepine, midazolam, to diazepam, both administered im for protection against diethyl-pnitrophenyl phosphate (paraoxon) toxicity. Adult male Sprague-D...

Antagonism of the discriminative stimulus properties of 10 mglkg cocaine was studied in rats by use of the dopamine Dl antagonist SCH 23390 and the Dl antagonist haloperidol. Whereas SCH 23390 and haloperidol were by themselves unable to antagonize the cueing properties of cocaine, the combination of both dopamine antagonists resulted in a complete blockade of the cocaine cue. In the presence o...

In this study, concentrations of cadmium using 3778 samples encompassing the total size Spain (about 505 km2) were investgated. Two novel spatial methods namely Moran eigenvector spatially varying coefficient (MESVC) and filtered unconditional quantile regression (SF-UQR) employed with aim avoiding problem local collinearity which is prevalent in models. Additionally, coefficients applied to as...

The effectiveness of 1,2-dimethyl-3-hydroxypyrid-4-one (Ll) in increasing iron excretion in iron-loaded patients improved the propsects for replacing desferrioxamine (DF) with an oral chelating drug.’,’ L1 belongs to a new group of iron chelators, the a-ketohydroxypyridines (KHP); which are cheap to p ~ e p a r e ~ . ~ and orally active. Recently, a detailed article by Porter et al.’ on in vivo...

Private vegetable gardens are often contaminated with elevated levels of heavy metals (HM). Bioindication, using the visible symptoms developing in leaves, can provide simple, cost-effective and reliable detection of soil pollution. In this experiment five species of vegetables from different families were exposed to soil contaminated with HM dust given as copper / zinc / cadmium/ lead = 640 /3...