The main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of Methocel® K15, Ethocel® standard 7FP premium, Eudragit ® RS100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. Risperidone floating tablets were formulated by wet granulati...

ABSTRACT
 In 2020 the number of cases Dengue Hemorrhagic Fever in Indonesia until 49th week reached 95,893 and caused death around 661 people. This study aims to obtain bestformula buccal film by optimizing concentration HPMC K15M Na. CMC evaluation characterization ofpreparations with 3 variations ratios against formulas on Na polymer excipients. include F1 0.67% : 0.33% ; F2 0.65% 0.5% F...

the main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of methocel® k15, ethocel® standard 7fp premium, eudragit ® rs100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. risperidone floating tablets were formulated by wet granulati...

In the current study, wet granulation with various concentrations and combinations of excipients like magnesium stearate as a lubricant, talc glident, DCP diluent, PVP K 30 binder successfully produced floating tablets rosiglitazone maleate. These included HPMC K15M, xanthan gum, sodium bicarbonate, tartaric acid gas-generating agents. We investigated every pre-compressional parameter, includin...

Plantain (Musa paradisiaca) starch,  prepared as crosslinked starch-urea (CSU), was utilized in the formulation of matrix tablets ambroxol hydrochloride. CSU synthesized by gelatinization plantain starch urea, with calcium chloride. Native and were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), chemical material properties. Ambroxol hydrochloride prepared CSU, ...

Melanoma is the most aggressive and lethal type of skin cancer, with a poor prognosis because of the potential for metastatic spread. The aim was to develop innovative powder formulations for the treatment of metastatic melanoma based on micro- and nanocarriers containing 5-fluorouracil (5FU) for pulmonary administration, aiming at local and systemic action. Therefore, two innovative inhalable ...

The main objective of this research investigational studies is to formulate floating matrix tablets glimipride by applying simplex centroid design for optimization technique and direct compression method. Centroid configuration was drilled as an enhancement strategy adjusting the amount three components all while holding back their total concentration constant. Ingredients HPMC K15m, Kappa-carr...

A round mutant of Escherichia coli, when grown in Methocel medium, forms chains of cells and does not form tetrads. This implies that successive division planes of the round mutant are parallel rather than perpendicular. These results differ from a previous proposal that division planes in this round mutant are perpendicular to the prior division plane (W. D. Donachie, S. Addinall, and K. Begg,...