OBJECTIVES Guidelines for the management of patients with metastatic bone disease (MBD) have been available to the orthopaedic community for more than a decade, with little improvement in service provision to this increasingly large patient group. Improvements in adjuvant and neo-adjuvant treatments have increased both the number and overall survival of patients living with MBD. As a consequenc...

Colorectal cancer (CRC) metastasis to the thyroid gland is rare. Here wereport a 45 yr-old man in western Iran referred to Hematology Clinic, Kermanshah city, Iran in March 2014 with complaint of exertional dyspnea, multi-nodular goiter as well as complaint of exertional dyspnea, and multi-nodular goiter. His history included a low anterior resection of rectum in 9 months ago for a high-risk st...

malignant tumors of the oral cavity which are metastatic are very rare and consist of 1% of malignancies of the oral cavity. numbness or paresthesia of the lower lip or the chin is the main feature of presence of metastasis in the jaw. our patient was a 38 year old woman with chief complaint of pain in the right half of her face, jaw and teeth. her medical history revealed a radical mastectomy ...

abstract: gestational trophoblastic neoplasm (gtn) is among rare human tumors which can be observed with widespread metastasis. two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. gtn was later diagnosed in both cases with brain metastasis. the first case: a 22 years old patient, admitted to the infectious disease ward, with probable...

Between 1969 and 1979, 90 patients of the Thoracic Surgical Unit at Harefield Hospital were found to have pulmonary metastatic disease. In 25 instances (28%) the diagnosis was established by bronchial biopsy. Twenty-four patients had endobronchial metastatic carcinoma and in one metastatic sarcoma was diagnosed. All but one had a past history of malignancy, the interval between treatment of the...

Metastatic bone disease is the most common malignancy of bone, it is estimated that 70% of all malignant bone tumors are metastatic in origin. At autopsy it has been reported between 30 to 85% of patients who die from cancer show occult skeletal metastases. Bone is the third most common site of metastatic process after lung and liver. 80% of metastatic bone disease arise from Ca of breast, pros...

the most common metastatic sites for colorectal carcinomas include the liver, lungs, brain, bones and peritoneal surfaces. in this report, a case of sigmoid colon carcinoma presented with cervical lymphadenopathy was detected with the help of pet/ct. a 57 year-old male presented with a complaint of swelling on the left side of his neck. ultrasonographic examination of the neck revealed three hy...

Background: Various studies have reported associations between frequencies of total peripheral blood lymphocytes and prostate cancer prognosis, but none so far has addressed the prognostic role CD8+ T-lymphocyte subsets. Methods: A 43 patients with metastatic disease 81 non-metastatic were included in this study. Flow cytometry analyses employed for determining Results: Statistically significan...

  Background and Objective: Oral cancer accounts for less than 3% of all cancers. Despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. Several studies have been performed to assess factors influencing lymph node metastasis and prognosis. The aim of this study was to evaluate some clinical and pathological factors influencing lymph ...