background: a soluble form of her-2/neu extracellular domain (sher-2) is reported to be released in the sera of metastatic breast cancer patients. objective: to measure the level of sher-2 in sera of 115 breast cancer patients. methods: serial samples of 27 patients with metastasis, 18 non-metastatic patients, 15 patients in stage 0/i and 14 patients with accompanying benign breast disease were...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: ca 15.3 is elevated in most patients with distant metastatic breast cancer who had prognostic information. the present study was performed to estimate predictive ability of ca 15.3 in assessment of symptomatic metastasis in patients with breast cancer. materials and methods: during five years, 159 primary breas...

only orchiectomy is still commonly used today either as a single therapy or in combination regimens. hypophysectomy & adrenalectomy showed such devastating effects on the endocrine equilibrium as to be inconsistent with an acceptable quality of life or even with survival. chemical adrenalectomy was also tried with drugs (eg. aminoglutethmide, spironolactone) leading to consequences superimposab...

Colorectal cancer remains one of the major cancer- related deaths despite progress in the treatment during past decades. Detection of disease at earlier stages reduces its mortality. The aim of current study was to investigate expression of Cytokeratin 19 (CK19), Cytokeratin 20 (CK20) and Guanylyl Cyclase C (GCC) mRNA in peripheral blood of non- metastatic colorectal cancer patients which may r...

A special form of prostate cancer is non-metastatic castration-resistant cancer. Patients with this have rising prostate-specific antigen and castrate testosterone levels, no radiological findings metastatic disease on computed tomography bone scan. The phase III trials demonstrated apalutamide, darolutamide or enzalutamide to be associated a significantly longer median metastasis-free survival...

Viola odorata as a medical herb is used in liver disorders and relieving cancer pain. In the present study, the cytotoxic, antioxidant, and anti-metastatic properties of Viola odorata hydro-alcoholic extract (VOE) were investigated in 4T1 breast cancer model. After treatment of 4T1 breast cancer cells with VOE, cell viability was measured by MTT assay. The implanted mice were treated with diffe...

Viola odorata as a medical herb is used in liver disorders and relieving cancer pain. In the present study, the cytotoxic, antioxidant, and anti-metastatic properties of Viola odorata hydro-alcoholic extract (VOE) were investigated in 4T1 breast cancer model. After treatment of 4T1 breast cancer cells with VOE, cell viability was measured by MTT assay. The implanted mice were treated with diffe...

breast cancer is the most common cancer in women except skin cancer. the common metastatic sites include lymph node, lung, liver and bone. however, metastasis to the bladder is extremely rare. to our knowledge, this is the first case of breast cancer metastasis to urinary bladder in jordan which is reported. nine years after the initial diagnosis of lobular breast carcinoma, the patient suffere...

The most common sites for metastases of colorectal cancer include the liver, lungs, brain, and regional lymph nodes. However, a limited number reported cases describe colon metastasis to thyroid gland. Metastatic adenocarcinoma gland is rare. majority these with are diagnosed years after initial treatment cancer. discovery usually made routine surveillance imaging, often patients have minimal o...