Hydrocortisone (100 mg in a single injection) was given to 120 pregnant women with threatened premature delivery. None was given to a control group of 40 mothers. Orciprenaline was also given to all the mothers to inhibit uterine activity. The administration of hydrocortisone did not accelerate delivery and in the treated group 55 babies were eventually born at term; none died or had perinatal ...

A complete atrioventricular block was seen in a nine year old girl in whom an infection with Borrelia burgdorferi was confirmed by serological testing. There were no other symptoms or cutaneous manifestations of the disease. Though a rash on the right ear was later recalled by her parents. The patient was treated with high dose penicillin and orciprenaline was given intermittently. The complete...

INTRODUCTION: Coronary artery bypass graft (CABG) surgery that is a basic revascularization method used commonly and hypertension appears frequently during after CABG operations. In the treatment of hypertension, metaproterenol sulfate (MS) one main agents; however, effects this agent on grafts are not known at an adequate level. The aim present study was to determine whether MS could be safely...

It has recently been shown that immunoglobulin (Ig)E facilitates the cholinergic bronchoconstrictor pathway in human tissue in vitro. However, whether this occurs in humans in vivo has not been clarified. In this study, the bronchodilator responses were examined to inhalation of a submaximal dose of the anticholinergic agent oxitropium bromide (600 microg) in normal and allergic subjects with v...

Asthnia treat i t’nt CII1I)hasizeS inhaled medication’ to manage airway inflalllluatiou.2 Because ofdifflculties encountered in the USC of metere(l-(lose inhalers (MDIs),3 ‘ mansphysicians recommend spacers.5’ A .56-year-old man with steroid-dependent asthma, vasculitis, and bilateral vision loss secondary to retinal artery ()cclusn)n used oral theophylline. oral pre(lniS 11e, and inhaled metap...

A molecular imprinted polymer (MIP) was computationally designed and synthesized for the selective extraction of metaproterenol (MTP), from human plasma. In this regards semi empirical MP3 and mechanical quantum (DFT) calculations were used to find a suitable functional monomers. On the basis of computational and experimental results, acrylic acid (AA) and DMSO:MeOH (90:10 %V/V) were found to b...

The bronchodilator effect of fenoterol hydrobromide (0.5, 1.25, and 2.5 mg) was compared with either isoproternol (2.8 mg) or isoetharine (5 mg) with phenylephrine (1.25 mg) in a double-blind placebo-controlled study. When delivered by an intermittent positive-pressure breathing device to 24 nonsmoking young adult asthmatic subjects, fenoterol produced significant improvement in forced expirato...

Neurobehavioral stress has been shown to promote tumor growth and progression and dampen the immune system. In this study, we investigated whether inhibiting stress hormone production could inhibit the development of mammary carcinoma and metastasis in a rat model of breast carcinogenesis. To enhance β-endorphin (BEP), the endogenous opioid polypeptide that boosts immune activity and decreases ...

The possibility of altered B-adrenergic receptors and/or adenyl cyclase activity in fibroblasts from patients with cystic fibrosis (CF) has been raised by several groups of investigators. Buchwald (1) reported a greater increase in CAMP’ after isoproterenol stimulation in CF than in normal fibroblasts and this was confirmed by Roscher et al. (2) for CF and normal fibroblasts in fresh medium. Fu...

BACKGROUND Permanent pacemaker implantation (PPMI) after transcatheter aortic valve implantation (TAVI) remains an issue open for criticism. Aim of this study is to investigate a strategy to reduce PPMI rate after TAVI in general and more specifically after implantation of the LOTUS® prosthesis. METHODS Through our learning curve, we have developed a structured protocol to reduce PPMI rate. T...