نتایج جستجو برای: metabolic activity
تعداد نتایج: 1311893 فیلتر نتایج به سال:
a “cocktail”of several probe drugs is often used to evaluate metabolic activity of multiple cytochrome p450 enzymes in one session. some interactions among probe drugs can appear and may impact the rate of biotransformation of other ones. our presented work was to aim on the influence of bupropion on rat cytochrome p450-mediated metabolism of tolbutamide. the biotransformation rates of tolbutam...
Introduction: Given to the fact that the high toxicity and side effects of chemotherapeutic drugs have limited their clinical use, it is not surprising that novel therapeutic drugs with less toxicity and more efficacy have entered into the novel protocols. Relatively, Melatonin, a main product of pineal gland, not only plays a key role in the regulation of circadian rhythm, but also exerts anti...
A “cocktail”of several probe drugs is often used to evaluate metabolic activity of multiple cytochrome P450 enzymes in one session. Some interactions among probe drugs can appear and may impact the rate of biotransformation of other ones. Our presented work was to aim on the influence of bupropion on rat cytochrome P450-mediated metabolism of tolbutamide. The biotransformation rates of tolbutam...
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