To investigate the prevalence and genotype-phenotype correlations of phosphatase tensin homolog induced putative kinase 1 (PINK1) variants in Parkinson's disease (PD) patients, we analyzed 1700 patients (842 familial PD 858 sporadic from Japanese origin). We screened entire exon exon-intron boundaries PINK1 using Sanger sequencing target by Ion torrent system. identified 30 with heterozygous va...

Page 1 of 23 Mercury Geochemistry in a Wetland and its Implications for In-situ Remediation 12/24/2008 http://sti.srs.gov/fulltext/ms2002056/ms2002056.html The objective of this study was to characterize the nature of Hg sorption on a wetland sediment with the intent of providing guidance for the selection of an appropriate in-situ remediation strategy. Total Hg concentrations in the sediments ...

We are looking at how new forms of document interface can be used to support new forms of scholarly discourse, and ultimately, new models of scholarly publishing. Towards this end, we have been using specially designed computer-meditated conferencing technology to realize an innovative peer review model within an academic e-journal – The Journal of Interactive Media in Education. In essence, th...

Meta-S is a practical implementation and extension of the theoretical framework developed by Hofstedt, which allows the user to attack problems requiring the cooperation of arbitrary domain-specific constraint solvers. Through its modular structure and its extensible strategy specification language it also serves as a test-bed for generic and problem-specific (meta-)solving strategies, which ar...

This chapter describes a comprehensive computational study on the template-assisted and Pd(OAc)2-catalyzed meta-selective C–H olefination reaction. The reaction mechanism, the active form of catalyst, the potential role of silver salt and the origin of meta-selectivity were investigated in this work. The computational results demonstrated that the conventionally proposed monomeric Pd(OAc)2 mode...