conclusions: about half the population in iran is infected with helicobacter pylori, the pollution in different areas and preventive strategies should be carried out to control this infection. the prevalence rate of helicobacter pylori infections in iran showed only little changes during the years 1994 to 2011. results: among the 30 studies evaluated, the prevalence rate of helicobacter pylori ...

to establish a comprehensive picture of the relationship between glutathione s-transferase omega 2 (gsto2; mim: 612314) gene n142d variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. studies published up to july 2012 with information about gsto2 polymorphism and breast cancer risk were identified using several electronic databases. we identified 4 eligible st...

background: acute promyelocytic leukemia (apl) is a unique subtype of acute leukemia. apl is a curable disease; however, drug resistance, early mortality, disease relapse and treatment-related complications remain challenges in apl patient management. one issue underlying these challenges is that the molecular mechanisms of the disease are not sufficiently understood. materials and methods: in ...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

leviteracetam (lev) is a novel antiepileptic drug with improved tolerance and safety, while carbamazepine (cbz) represents classical antiepileptic drugs. so far, a systemic comparison of the efficacy and side effects of these two drugs is lacking. a literature review on the comparison of leviteracetam versus carbamazepine for patients with epilepsy was performed up to september 2013 using pubme...

introduction: enuresis is the second most common disorder among children after allergic disorders. according to the results of previous studies, different estimates of enuresis prevalence and its related factors have been reported. combining the results of these studies is valuable. this study aims to estimate the prevalence of enuresis and its related factors among iranian children.materials a...

conclusions cp is effective for inducing clinical response and maintenance of clinical remission in patients with moderate to severe cd with similar side-effect profile as the control arms. background tumor necrosis factor-α (tnf-α) antibodies are currently used in patients with moderate to severe crohn’s disease (cd) who are unresponsive to conventional therapies. certolizumab pegol (cp) is on...

obesity is one of the main public health problems which underlie many chronic illnesses and socioeconomic difficulties. according to the literature review, there are limited data on the prevalence of obesity in different parts of iran as well as its trend and prevalence among different age and gender groups. the aim of this study was to estimate the obesity prevalence in iran using meta-analysi...

conclusions primary dysmenorrhea is a common problem in iran however, there are only a few studies regarding secondary dysmenorrhea prevalence. moreover, there is a significant variation between the results of the studies on the primary dysmenorrhea prevalence. therefore, further evidence-based data on national studies is needed to estimate the exact estimation of dysmenorrhea prevalence in ira...

smoking is known as a major cause of chronic obstructive pulmonary disease (copd) and hence immediate and effective interventions are required for its elimination. this study aimed to collect valid data with regard to cigarette smoking in adult population of north of iran for policy making by a meta-analysis of the documents of national non-communicable disease risk factors surveillance system....